Results 91 to 100 of about 510,744 (297)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Human vaccines & immunotherapeutics: News June 2023
Human Vaccines & Immunotherapeutics, 2023 Ronald Ellis, Adam Weiss
doaj +1 more source
A Practical Perspective on Human Capital Post Merger Integration in Central and Eastern Europe [PDF]
Driven by a philosophy of shareholder value, mergers and acquisitions form a new economic, social and cultural environment. It is only by a profound understanding of the success factors in mergers and acquisitions that they are able to improve ...
Marian-Adrian GROSU +1 more
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Human vaccines & immunotherapeutics: News January 2023
Human Vaccines & Immunotherapeutics, 2023 Ronald Ellis, Adam Weiss
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Human vaccines & immunotherapeutics: News August 2023
Human Vaccines & Immunotherapeutics, 2023 Ronald Ellis, Adam Weiss
doaj +1 more source
An analysis of mergers and acquisitions in the Turkish banking sector [PDF]
We explore various aspects of mergers and acquisitions in the banking industry within a simple model that allows explicit comparison of sector performance before and after the mergers and acquisitions.
Mumcu, Ayşe, Zenginobuz, Unal
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Human vaccines & immunotherapeutics: News October 2023
Human Vaccines & Immunotherapeutics, 2023 Ronald Ellis, Adam Weiss
doaj +1 more source