Results 151 to 160 of about 508,488 (299)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

ACQUISITIONS [PDF]

Bulletin of the Detroit Museum of Art, 1915
openaire   +3 more sources

Correction: Integrated multidisciplinary analysis of mobile digital radiographic acquisitions of the mummies of the Hermits from the Sanctuary of Madonna della Corona (Italy - 17th to 19th Century CE). [PDF]

Front Med (Lausanne)
Larentis O, Gorini I, Campus M, Lorenzetti M, Mansueto G, Bortolotto S, Zappa E, Gregorini A, Rampazzi L, Vanin S, Carta G, Carli A, Simonaitis L, De Luca L, Tonina E.   +14 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

HV&I Reviewer Highlight

Human Vaccines & Immunotherapeutics
Ronald Ellis, Adam Weiss
doaj   +3 more sources

Repeatability and reproducibility of quantitative ultrasound cervical measurements in women at risk for preterm birth. [PDF]

Discov Imaging
Villegas-Downs M, Gao Z, Jia H, Han A, McFarlin BL, O'Brien WD, Simpson DG.   +6 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Acquisitions: The Print Room

The Rijksmuseum Bulletin, 2011
openaire   +4 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Assessment of Image Quality Performance of a Photon-Counting Computed Tomography Scanner Approved for Whole-Body Clinical Applications. [PDF]

Sensors (Basel)
Maddaloni FS, Sarno A, Loria A, Piai A, Lenardi C, Esposito A, Del Vecchio A.   +6 more
europepmc   +1 more source