Results 161 to 170 of about 97,766 (255)

Short Dynamic 68 GA-PSMA PET Reconstruction to Differentiate Urinary Excretion From Extra-urinary Uptakes With LAFOV-PET. [PDF]

Clin Nucl Med
Delhom L, Bourhis D, Delcroix O, Robin P, Querellou S.   +4 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Optimal acquisition time of [⁶⁸Ga]Ga-PentixaFor PET/CT for initial staging of multiple myeloma: an ancillary study to the PentiMyelo protocol. [PDF]

EJNMMI Res
François C, Carlier T, Touzeau C, Janz A, Dubégny C, Jamet B, Kraeber-Bodéré F, Bailly C, Bodet-Milin C.   +8 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Design of Differential Single-Block and Multi-Block Presaturated Ultrashort Echo Time Pulse Sequences for Fast and Flexible Short-T₂ Imaging. [PDF]

Magn Reson Med
Reich JA, Taylor SL, Harkins KD, Crescenzi RL, MacMillan EL, Feldman RE.   +5 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Large gains in SNR through the application of Shinnar-Le Roux RF pulse design to short-TR spin-echo fMRI acquisitions at 7 T. [PDF]

Magn Reson Imaging
Balasubramanian M, Mulkern RV, Grissom WA, Polimeni JR.   +3 more
europepmc   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

Human vaccines and immunotherapeutics: News August 2024

Human Vaccines & Immunotherapeutics
Ronald Ellis, Adam Weiss
doaj   +1 more source

Reducing Inhomogeneous MT (ihMT) Acquisition Time Using Frequency Alternation at Low Duty Cycle for Single Offset (FALSO) MT Preparations. [PDF]

Magn Reson Med
Varma G, Grant AK, Soustelle L, Girard OM, Duhamel G, Alsop DC.   +5 more
europepmc   +1 more source