Results 181 to 190 of about 515,071 (299)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

HV&I Reviewer Highlight

Human Vaccines & Immunotherapeutics
Ronald Ellis, Adam Weiss
doaj   +5 more sources

Ultra-fast MRI for brain-age prediction in a real-world cognitive disorders clinic. [PDF]

Front Aging Neurosci
Navarro-González R, de Luis-García R, Aja-Fernández S, Liu W, Alexander DC, Barkhof F, Beament M, Chughtai HR, Fox NC, Mummery CJ, Rosa-Grilo M, Thomas DL, Parker GJM, Cole JH.   +13 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Influence of retinal eccentricity, color blindness, and age on optoretinography measured with AOSLO. [PDF]

Biomed Opt Express
Granier J, Gofas Salas E, Grieve K.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Optimization of Image Quality for Quantitative Multi-Contrast Atherosclerosis Characterization (qMATCH): Comparison Between Transverse and Coronal Acquisitions. [PDF]

AJNR Am J Neuroradiol
Hsu YC, Lu M, Llanes A, Keushkerian MJ, Nguyen KL, Johnson K, Altbach MI, Morris HD, DeMarco JK, Deshpande V, Mitsouras D, Saloner D, McNally S, Kim SE, Roberts J, Hadley R, Treiman GS, Parker DL, Li D, Xie Y.   +19 more
europepmc   +1 more source

ACQUISITIONS [PDF]

Bulletin of the Detroit Museum of Art, 1913
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Human vaccines and immunotherapeutics: News January 2024

Human Vaccines & Immunotherapeutics
Ronald Ellis, Adam Weiss
doaj   +1 more source