International survey in four European countries on diagnostic reference levels based on clinical indications in computed tomography. [PDF]
Schegerer AA +16 more
europepmc +1 more source
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Timely and Efficient Infant Diagnosis Is Required to End AIDS in Children. [PDF]
Vojnov L, Jani IV.
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Human Vaccines and Immunotherapeutics: News October 2025
Ronald Ellis, Adam Weiss
doaj +1 more source
Associations between food insecurity and Supplemental Nutrition Assistance Program participation with ultra-processed food acquisitions for home consumption in US households. [PDF]
Fulay A +6 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
A dense longitudinal multimodal single-subject rs-fMRI dataset acquired by self-administered scanning. [PDF]
Petrovskiy ED.
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
A tissue-informed deep learning-based method for positron range correction in preclinical [Formula: see text]Ga PET imaging. [PDF]
Encina-Baranda N +7 more
europepmc +1 more source

