Results 181 to 190 of about 213,692 (300)

Human vaccines and immunotherapeutics: News January 2024

open access: yesHuman Vaccines & Immunotherapeutics
Ronald Ellis, Adam Weiss
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Human vaccines and immunotherapeutics: News February 2025

open access: yesHuman Vaccines & Immunotherapeutics
Ronald Ellis, Adam Weiss
doaj   +1 more source

Prospective estimation of water equivalent diameter and SSDE using 3D landmark CT scans. [PDF]

open access: yesJ Appl Clin Med Phys
Hernandez AM   +6 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Human vaccines and immunotherapeutics: News December 2024

open access: yesHuman Vaccines & Immunotherapeutics
Ronald Ellis, Adam Weiss
doaj   +1 more source

Biodistribution and dosimetry of the carbon-11 labelled PARP1-selective PET radiopharmaceutical [<sup>11</sup>C]AZ14193391. [PDF]

open access: yesEJNMMI Res
Törnblom A   +10 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Hospital System Acquisition of Physician Practices.

open access: yesJAMA Netw Open
Young GJ   +4 more
europepmc   +1 more source

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