Results 191 to 200 of about 213,692 (300)

Ultrasensitive detection of lung inflammation in male mice using immuno-magnetic particle imaging. [PDF]

Nat Commun
Pedron S, Martinez de Lizarrondo S, D'Arco L, Malherbe J, Trébel S, Tashkandi J, Alt K, Galy B, Bellaye PS, Vigne J, Vivien D, Gauberti M, Bonnard T.   +12 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Human vaccines and immunotherapeutics: News April 2025

Human Vaccines & Immunotherapeutics
Ronald Ellis, Adam Weiss
doaj   +1 more source

Reimagining Hepatitis C Elimination: Time for Actions, Not Targets. [PDF]

J Int AIDS Soc
Klein MB, Kronfli N, Young J.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Human vaccines and immunotherapeutics: News June 2025

Human Vaccines & Immunotherapeutics
Ronald Ellis, Adam Weiss
doaj   +1 more source

Multi-Contrast Human Brain CEST MRI at 11.7 T: First In Vivo Demonstration. [PDF]

Magn Reson Med
Ressam C, Brégeat J, Lopez Kolkovsky AL, Amadon A, Vignaud A, Massire A, Chu S, Gunamony S, Boulant N, Gras V, Mauconduit F, Ciobanu L.   +11 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Human vaccines and immunotherapeutics: News September 2025

Human Vaccines & Immunotherapeutics
Ronald Ellis, Adam Weiss
doaj   +1 more source

Physiological adaptation of the jugular venous pulse during long-duration spaceflight. [PDF]

Sci Rep
Zamboni P, Pagani A, Bertagnon A, Fanciulli G, Proto A, Zamboni M, Brancaccio R, Taibi A.   +7 more
europepmc   +1 more source