Acrolein contributes to human colorectal tumorigenesis through the activation of RAS-MAPK pathway
Scientific Reports, 2021 Colorectal cancer (CRC) is one of the most well-known malignancies with high prevalence and poor 5-year survival. Previous studies have demonstrated that a high-fat diet (HFD) is capable of increasing the odds of developing CRC.
Hong-Chieh Tsai +11 more
doaj +1 more source
A self optimizing synthetic organic reactor system using real-time in-line NMR spectroscopy [PDF]
, 2015 A configurable platform for synthetic chemistry incorporating an in-line benchtop NMR that is capable of monitoring and controlling organic reactions in real-time is presented.
Cronin, Leroy +3 more
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Food Chemistry: X, 2022 The effect of acrolein on the formation of the 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) was investigated in a chemical model. Acrolein was found to increase PhIP formation at each tested addition level. 0–0.2 mmol of acrolein increased PhIP
Meilin Jing +5 more
doaj +1 more source
Elemental composition and oxidation of chamber organic aerosol [PDF]
, 2011 Recently, graphical representations of aerosol mass spectrometer (AMS) spectra and elemental composition have been developed to explain the oxidative and aging processes of secondary organic aerosol (SOA).
Canagaratna, M. R. +7 more
core +2 more sources
Acute Acrolein Exposure Induces Impairment of Vocal Fold Epithelial Barrier Function. [PDF]
PLoS ONE, 2016 Acrolein is a ubiquitous pollutant abundant in cigarette smoke, mobile exhaust, and industrial waste. There is limited literature on the effects of acrolein on vocal fold tissue, although there are clinical reports of voice changes after pollutant ...
Xinxin Liu +2 more
doaj +1 more source
The Role of Acrolein in Neurodegenerative Diseases and Its Protective Strategy
Foods, 2022 Neurodegenerative diseases are characterized by a massive loss of specific neurons, which can be fatal. Acrolein, an omnipresent environmental pollutant, is classified as a priority control contaminant by the EPA.
Xinxin Chang +9 more
doaj +1 more source
Applications of the Conceptual Density Functional Theory Indices to Organic Chemistry Reactivity [PDF]
, 2016 Indexación: Web of ScienceTheoretical reactivity indices based on the conceptual Density Functional Theory (DFT) have become a powerful tool for the semiquantitative study of organic reactivity.
Domingo, Luis R. +2 more
core +2 more sources
Neurobiology of Pain, 2017 Exposure to airborne toxins can trigger headaches, but the mechanisms are not well understood. Some environmental toxins, such as acrolein, activate transient receptor potential ankyrin 1 (TRPA1), a receptor involved in pain sensation that is highly ...
Emma Leishman +7 more
doaj +1 more source
Unilateral Microinjection of Acrolein into Thoracic Spinal Cord Produces Acute and Chronic Injury and Functional Deficits [PDF]
, 2016 Although lipid peroxidation has long been associated with spinal cord injury (SCI), the specific role of lipid peroxidation-derived byproducts such as acrolein in mediating damage remains to be fully understood.
Brenia, John +12 more
core +1 more source
Experimental and modeling study of the low-temperature oxidation of large alkanes [PDF]
, 2008 This paper presents an experimental and modeling study of the oxidation of large linear akanes (from C10) representative from diesel fuel from low to intermediate temperature (550-1100 K) including the negative temperature coefficient (NTC) zone.
Battin-Leclerc, Frédérique +4 more
core +3 more sources