Results 81 to 90 of about 32,466 (225)
Pathological Role of Unsaturated Aldehyde Acrolein in Diabetic Retinopathy
Frontiers in Immunology, 2020 With increasing prevalence of diabetes and a progressively aging society, diabetic retinopathy is emerging as one of the global leading causes of blindness.
Miyuki Murata +5 more
doaj +1 more source
Kinetics and mechanism of protein tyrosine phosphatase 1B inactivation by acrolein [PDF]
, 2007 Human cells are exposed to the electrophilic [alpha],[beta]-unsaturated aldehyde acrolein from a variety of sources. The reaction of acrolein with functionally critical protein thiol residues can yield important biological consequences.
Gates, Kent S. (Kent Stephen), 1962- +2 more
core +1 more source
Journal of Oral Pathology &Medicine, EarlyView.ABSTRACT Background Early‐onset oral squamous cell carcinoma (EO‐OSCC), commonly defined as occurring in individuals under 50 years of age, is increasingly recognized as a potentially distinct clinical subset with differences in exposure patterns and tumor biology compared with conventional oral squamous cell carcinoma (OSCC).
Gennaro Musella +8 more
wiley +1 more source
Comparison of C═C bond hydrogenation in C-4 unsaturated nitriles over Pt/alumina [PDF]
, 2016 The hydrogenation of allyl cyanide (but-1-ene-4-nitrile, AC), trans- and cis-crotononitrile (E- and Z-but-2-ene nitrile, TCN and CCN), and methacrylonitrile (2-cyano-1-propene, MCN) were studied, both singly and competitively, over a Pt/alumina catalyst ...
Andrew Monaghan +3 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley +1 more source
Advanced Science, 2021 Increased acrolein (ACR), a toxic metabolite derived from energy consumption, is associated with diabetes and its complications. However, the molecular mechanisms are mostly unknown, and a suitable animal model with internal increased ACR does not exist ...
Haozhe Qi +14 more
doaj +1 more source
Analytical Science Advances, Volume 7, Issue 1, June 2026.ABSTRACT This study investigated the prevalence of electronic smoking device (ESD) use and its associated behavioural and chemical risks among university students in Bahia, Brazil. A cross‐sectional survey was conducted with 355 students from public and private institutions through an online questionnaire between April and May 2023. Among participants,
Eduard F. Valenzuela +7 more
wiley +1 more source
Quantitative representation of reactivity, selectivity and site activation concepts in organic chemistry [PDF]
, 2004 Indexación: ScieloReactivity, selectivity and site activation are classical concepts in chemistry which are amenable to quantitative representation, in terms of static global, local and non local density response functions.
Contreras, Renato R. +2 more
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Food Frontiers, Volume 7, Issue 3, May 2026.Integrative metabolomic and transcriptomic analyses revealed the chemical and molecular basis of aroma divergence in fruits of three Isatis species. Distinct volatile profiles and 44 key aroma‐active compounds defined species‐specific sensory characteristics, while co‐expression analysis identified NAC transcription factors and lipid‐derived pathway ...
Rong Chen +10 more
wiley +1 more source
Hesperetin mitigates acrolein-induced apoptosis in lung cells in vitro and in vivo
Redox Report, 2018 Objectives: A number of studies have suggested that acrolein-induced lung injury and pulmonary diseases are associated with the depletion of antioxidants and the production of reactive oxygen species.
Jung Hyun Park +2 more
doaj +1 more source