Results 181 to 190 of about 4,287,423 (312)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Widespread Lateral Transmission in <i>Fergusonina</i> Galling Flies (Diptera: Fergusoninidae) and Their Obligate Nematode Mutualists Does Not Preclude an Overall Pattern of Cospeciation. [PDF]

Ecol Evol
Scheffer SJ, Lewis ML, Davies KA, Giblin-Davis RM, Taylor GS, Nelson LA, Purcell MF, Makinson JR, Ye W, Omland KE, Yeates DK.   +10 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Smartphone-Based Acceptance and Commitment Therapy for Postmastectomy Pain Syndrome: A Pilot RCT Evaluating Feasibility, Acceptability, and Preliminary Clinical Outcomes. [PDF]

J Pain Res
Sakai M, Toyama T, Hashimoto H, Ueno T, Wanifuchi-Endo Y, Fujita T, Asano T, Horisawa N, Uchida M, Akechi T.   +9 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

The p53 proto-oncogene can act as a suppressor of transformation.

Cell, 1989
C. Finlay, P. Hinds, A. Levine
semanticscholar   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Climate change boredom: Exploring its predictors and the psychological factors that influence intention to act. [PDF]

PLoS One
Petrescu-Mag RM, Petrescu DC, Rastegari H, Ivan A, Petrescu-Mag IV.   +4 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Acceptance and commitment therapy (ACT)-based programs for reducing symptoms of depression, anxiety and/or stress applied to the educational context: An exploratory review. [PDF]

PLOS Ment Health
Pedraza Palacios JA.
europepmc   +1 more source