Results 321 to 330 of about 213,915 (375)
Some of the next articles are maybe not open access.
Isolated ACTH deficiency confirmed by ACTH radioimmunoassay
Journal of Endocrinological Investigation, 1980A 28 year old woman presented with symptoms and biochemical findings suggesting hypoglycemia. Detailed endocrine investigations indicated secondary adrenocortical insufficiency with no rise in plasma ACTH or plasma cortisol following insulin-induced hypoglycemia or vasopressin infusion.
T C, Ooi +3 more
openaire +2 more sources
ACTH precursors characterize the ectopic ACTH syndrome
Clinical Endocrinology, 1994SummaryOBJECTIVE ACTH is secreted by the pituitary following processing of larger molecular weight precursors, proopiomelanocortin and pro‐ACTH. Ectopic ACTH syndrome refers to the secretion of ACTH by non‐pituitary tumours, but the predominant circulating form of proopiomelano‐cortin‐related peptides remains unclear.PATIENTS Fifteen patients with ...
Stewart, P. M. +9 more
openaire +3 more sources
ACTH-Secreting Pheochromocytoma with False-Negative ACTH Immunohistochemistry
Endocrine Pathology, 2012Since 1955, when Roux published the first association between pheochromocytoma and Cushing’s syndrome, we have come to appreciate the unique features of this unusual clinical entity. Pheochromocytoma represents a rare cause of hypercortisolism, accounting for less than 5 % of ectopic Cushing’s syndrome while less than 1 % of pheochromocytomas is ...
M. F. Cassarino +6 more
openaire +5 more sources
Clinical and Experimental Hypertension. Part A: Theory and Practice, 1984
(1984). Acth Dependent Hypertension. Clinical and Experimental Hypertension. Part A: Theory and Practice: Vol. 6, No. 3, pp. 599-646.
B A, Scoggins +3 more
openaire +2 more sources
(1984). Acth Dependent Hypertension. Clinical and Experimental Hypertension. Part A: Theory and Practice: Vol. 6, No. 3, pp. 599-646.
B A, Scoggins +3 more
openaire +2 more sources
Clinical Endocrinology, 1991
Summary. Isolated ACTH deficiency is a rare disorder. We report four cases of this disease which presented to the Department of Endocrinology at Leeds General Infirmary over a one‐year period. The diagnostic clinical and biochemical features of each case are discussed and the pertinent literature is reviewed.
S M, Orme, P E, Belchetz
openaire +2 more sources
Summary. Isolated ACTH deficiency is a rare disorder. We report four cases of this disease which presented to the Department of Endocrinology at Leeds General Infirmary over a one‐year period. The diagnostic clinical and biochemical features of each case are discussed and the pertinent literature is reviewed.
S M, Orme, P E, Belchetz
openaire +2 more sources
Baillière's Clinical Endocrinology and Metabolism, 1996
The ACTH-R is a receptor that has a prominent role in mammalian physiology, but which has been notoriously difficulty to study. The cloning of the gene encoding this receptor in 1992 should permit significant advances in the understanding of the physiology, pharmacology and pathophysiology of ACTH.
A J, Clark, F M, Cammas
openaire +2 more sources
The ACTH-R is a receptor that has a prominent role in mammalian physiology, but which has been notoriously difficulty to study. The cloning of the gene encoding this receptor in 1992 should permit significant advances in the understanding of the physiology, pharmacology and pathophysiology of ACTH.
A J, Clark, F M, Cammas
openaire +2 more sources
The Journal of Steroid Biochemistry and Molecular Biology, 1995
Ectopic ACTH syndrome represents a cancer-induced amplification of a property [proopiomelanocortin (POMC) peptides production] normally present in the cells from which the cancer originated but with aberrant posttranslational processing of POMC resulting in a greatly elevated secretion of ACTH precursors.
B L, Wajchenberg +5 more
openaire +2 more sources
Ectopic ACTH syndrome represents a cancer-induced amplification of a property [proopiomelanocortin (POMC) peptides production] normally present in the cells from which the cancer originated but with aberrant posttranslational processing of POMC resulting in a greatly elevated secretion of ACTH precursors.
B L, Wajchenberg +5 more
openaire +2 more sources
Hormone Research in Paediatrics, 1998
Isolated ACTH is a rare cause of secondary adrenocortical insufficiency. The diagnosis is made by the demonstration of low cortisol production with low plasma ACTH, absent adrenal responses to stimulation for pituitary or hypothalamus with intact adrenal response to exogenous ACTH, and normal secretory indices of other pituitary hormones.
D A, de Luis, R, Aller, E, Romero
openaire +2 more sources
Isolated ACTH is a rare cause of secondary adrenocortical insufficiency. The diagnosis is made by the demonstration of low cortisol production with low plasma ACTH, absent adrenal responses to stimulation for pituitary or hypothalamus with intact adrenal response to exogenous ACTH, and normal secretory indices of other pituitary hormones.
D A, de Luis, R, Aller, E, Romero
openaire +2 more sources
The Journal of Pediatrics, 1980
A 9 1/2-year-old girl is presented who had cyclical attacks of abdominal pain, vomiting, emotional disturbance, and marked weight change for two years. Associated findings were facial plethora, hypertension, transient hyperglycemia and glycosuria, elevated plasma ACTH, cortisol, and urinary 17-OHCS excretion, and low plasma osmolality with hyponatremia.
T, Sato +5 more
openaire +2 more sources
A 9 1/2-year-old girl is presented who had cyclical attacks of abdominal pain, vomiting, emotional disturbance, and marked weight change for two years. Associated findings were facial plethora, hypertension, transient hyperglycemia and glycosuria, elevated plasma ACTH, cortisol, and urinary 17-OHCS excretion, and low plasma osmolality with hyponatremia.
T, Sato +5 more
openaire +2 more sources