Results 101 to 110 of about 4,470,426 (294)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Imagination and creativity

open access: yesПроблеми на постмодерността, 2014
House of Baba Yaga, there is of course only in fairy tales, but the elements that built this magical image, taken from the real experience of people and just combining them bears the marks of the fairy, ie imagination has become the primary cause of ...
Milena Aneva
doaj  

The Economics of 'Acting White' [PDF]

open access: yes
This paper formalizes a sociological phenomenon entitled 'acting white'. The key idea is that individuals face a tension between signaling their type to the outside labor market and signaling their type to a peer group: signals that induce high wages can
David Austen-Smith, Roland G. Fryer
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Fából vaskarika. Tudunk mi valamit a színészetről?

open access: yesSymbolon, 2017
Squaring the Circle. What is our knowledge of acting? Or maybe we should not ask ourselves what, but where is our knowledge in relation to acting? Does it precede it or does it actually help us rediscover acting again and again?
András Hatházi
doaj  

The concept “plastic culture” in the context of acting

open access: yesКультура України
A person exists in a certain cultural environment and is always adapting to it. The human need for movement and self-expression contributes to the development of sports, theater, dance, and pantomime.
N. Ihnatieva
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

‘Essere, o non essere’ in scena. Sull’orma creativa di Adelaide Ristori

open access: yesDrammaturgia
From an original perspective, this essay delves into the significance of Adelaide Ristori’s entrances and exits from the stage, the value that the Grande Attrice used to attribute to such crucial scenic moments and her expectations of national and ...
Teresa Megale
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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