Results 141 to 150 of about 1,553,784 (316)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Oyunculuk Eğitiminde Nörobilimsel Temellerin Kullanımı: Pratik Bir Yaklaşım Olarak Nörosomatik Oyunculuk

open access: yesArt Vision
Bu makale, Kartezyen ikilik ve semiyolojinin tiyatro uygulamalarını etkileyen bakış açılarını, oyuncuların ve seyircilerin deneyimlerini tanımlayan fenomenolojik boyutları, süreç ve performansın bedenleşmiş doğasını, somatik yaklaşımların dönüştürücü ...
Fatoş Su Özkarataş
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Use of Long-Acting Injectables Versus Oral Antipsychotics Among Indigent Populations: A Systematic Review [poster]

open access: yes, 2022
Introduction: Schizophrenia affects approximately 3,810,000 people in the United States and is estimated to cost $155.7 billion. It increases unemployment and poverty, and it is estimated that as much as 25% of the homeless population has schizophrenia ...
Ryan, Brooke
core  

Volver a Casa. Seminario de Teatro sobre la técnica de la fuerza ausente. Dictado por Pompeyo Audivert. Una reseña de lo vivenciado

open access: yesEl Peldaño
En la siguiente reseña se intenta trasmitir la experiencia vivenciada en “Volver a Casa”. Seminario de Teatro sobre la técnica de la fuerza ausente, dictado por Pompeyo Audivert.
Verónica Ana Eva Rodríguez
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Acting theory as poetic of drama: A study of the emergence of the concept of 'motivated action' in playwriting theory

open access: yes, 2012
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Playwriting theory has, from its beginning, been concerned with the search for the essential nature of dramatic writing.
Ferreira de Mendonça, Guilherme Abel
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Relative nutritional deficiencies associated with centrally acting monoamines

open access: yes, 2012
Marty Hinz1, Alvin Stein2, Thomas Uncini31Clinical Research, NeuroResearch Clinics Inc, Cape Coral, 2Stein Orthopedic Associates, Plantation, FL, 3DBS Labs, Duluth, MN, USABackground: Two primary categories of nutritional deficiency exist.
Hinz M, Stein A, Uncini T
core  

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