Results 161 to 170 of about 60,978 (218)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source
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To Act or Not to Act, That Is the Question

The American Journal of Bioethics, 2019
Lars Oystein Ursin’s article, “Withholding and Withdrawing Life-Sustaining Treatment: Ethically Equivalent?” (Ursin 2019), and Dominic Wilkinson, Ella Butcherine, and Julian Savulescu’s article, “W...
openaire   +3 more sources

ON ACTING AND NOT-ACTING

The Drama Review, 1972
Acting means to feign, to simulate, to represent, to impersonate. As Happenings demonstrated, not all performing is acting. Although acting was sometimes used, the performers in Happenings generally tended to “be” nobody or nothing other than themselves; nor did they represent, or pretend to be in, a time or place different than that of the spectator ...
openaire   +1 more source

Motor cortex — to act or not to act?

Nature Reviews Neuroscience, 2017
The motor cortex is a large frontal structure in the cerebral cortex of eutherian mammals. A vast array of evidence implicates the motor cortex in the volitional control of motor output, but how does the motor cortex exert this 'control'? Historically, ideas regarding motor cortex function have been shaped by the discovery of cortical 'motor maps ...
Christian Laut, Ebbesen, Michael, Brecht
openaire   +2 more sources

Acting/Non-Acting

Performance Art Magazine, 1979
motives ranging from ideology to ignoTen years ago it was fantastic that, as a work raneo. But almost overnight, performance of art, art could be a live event. But within a activity has shifted from coafessional and couple of years, that in itself was no longer formal geetmess to theatrical entertainenough.
Scott Burton   +4 more
openaire   +1 more source

Act up? Act out? ACT!

The Brown University Child and Adolescent Behavior Letter, 2017
Some of you will have heard of plain old cognitive therapy (CT) and rational emotive therapy (RET), dating back to the pathbreaking work of Aaron Beck and Albert Ellis. Most of you will have heard of cognitive behavioral therapy (CBT), an enhancement of cognitive therapy alone (and why RET later became REBT).
openaire   +1 more source

Acting to understand and understanding to act

Kybernetes, 2014
Purpose – To establish the essential centrality of a circular relationship between acting and understanding, and a role learning plays in this circularity, with special reference to Aristotle's phronesis and sophia. The purpose of this paper is to establish a position.
openaire   +1 more source

Acting Autonomously Versus not Acting Heteronomously

Theory and Decision, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +4 more sources

Act without Acting

2021
This chapter is the translation of chapter 63 of the Expository Commentary to the Daode jing by Cheng Xuanying. Cheng reads the ancient Daode jing in the light of early Tang dynasty Daoism. In the early medieval period up to the Tang, Daoism had developed in close contact with Buddhism, adopting and co-opting many concepts and ideas from Buddhism ...
openaire   +1 more source

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