Immune-mediated changes in actinic keratosis following topical treatment with imiquimod 5% cream
Background The objective of this study was to identify the molecular processes responsible for the anti-lesional activity of imiquimod in subjects with actinic keratosis using global gene expression profiling.
Raghavan Shalini +9 more
doaj +1 more source
Actinic keratosis is considered a precancerous lesion, constituting a precursor to squamous cell carcinoma (SCC) formation. Perineural invasion has been observed in patients with cutaneous carcinoma due to local subcutaneous tissue destruction and ...
Edgard Farah +6 more
doaj +1 more source
British Association of Dermatologists and British Photodermatology Group guidelines for topical photodynamic therapy 2018 [PDF]
The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the use of topical photodynamic therapy (PDT). The document aims to: • offer an appraisal of all relevant literature up to April 2018, focusing on any key
Collier, Nick +12 more
core +2 more sources
Xeroderma Pigmentosum: a case report with oral implications [PDF]
Xeroderma Pigmentosum is a rare autosomal recessive genetic disorder characterized by defective DNA repair leading to clinical and cellular hypersensitivity to ultraviolet radiation and carcinogenic agents.
Antônio Barreto, Jaison +5 more
core +1 more source
Actinic keratosis is a common skin disease that may progress to invasive squamous cell carcinoma if left untreated. Ingenol mebutate has demonstrated efficacy in field treatment of actinic keratosis.
Sonia Segura +7 more
doaj +1 more source
A novel light source with tuneable uniformity of light distribution for artificial daylight photodynamic therapy [PDF]
This project was supported by the University of St. Andrews through the Science and Technology Facilities Council (STFC) Impact Accelerator Award (IAA) and by the Laser Research and Therapy Fund (registered charity SC030850). P O’M is funded by Medi-lase
Brown, C. Tom A. +5 more
core +3 more sources
The more the better? An appraisal of combination therapies for actinic keratosis
Actinic keratoses (AK) are common precancerous lesions of the skin. Numerous interventions exist for the treatment of AK, including lesion‐ and field‐directed approaches.
Theresa Steeb +5 more
semanticscholar +1 more source
A fluorescing spot on the temple: a helpful reminder for a detailed history and physical exam [PDF]
We discuss a woman with a history of non-melanoma skin cancer who presented with a new erythematous macule on her right temple. On examination with Wood lamp the well-demarcated macule fluoresced pink making neoplasm unlikely.
Neiner, Destiny +3 more
core
Safety and efficacy of vismodegib in patients aged ≥65 years with advanced basal cell carcinoma. [PDF]
Because many patients with unresectable basal cell carcinoma (BCC) are aged ≥65 years, this study explores the efficacy and safety of vismodegib in these patients with locally advanced (la) or metastatic (m) basal cell carcinoma (BCC) in the ERIVANCE BCC
Arron, Sarah +8 more
core +2 more sources
White-light oblique-incidence diffuse reflectance spectroscopy for classification of in-vivo pigmented skin lesions [PDF]
A study of in-vivo classification of pigmented skin lesions using oblique-incidence diffuse reflectance spectroscopy is presented. Spatio-spectral data in the wavelength range from 455 to 765 nm are collected from 111 pigmented lesions including 10 ...
Duvic, Madeleine +3 more
core

