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Actinic keratosis is a cutaneous lesion characterized by proliferation of atypical epidermal keratinocytes due to prolonged exposure to exogenous factors such as ultraviolet radiation. AKs are in-situ-squamous cell carcinomas (PEC) of the skin. AK typically presents as erythematous, scaly patch or papule (classic AK), occasionally as thick, adherent ...
D, Dejaco +3 more
+8 more sources
Explainable human‐in‐the‐loop healthcare image information quality assessment and selection
Abstract Smart healthcare applications cannot be separated from healthcare data analysis and the interactive interpretability between data and model. A human‐in‐the‐loop active learning approach is introduced to reduce the cost of healthcare data labelling by evaluating the information quality of unlabelled medical data and then screening the high ...
Yang Li, Sezai Ercisli
wiley +1 more source
Innovative Agents for Actinic Keratosis and Nanocarriers Enhancing Skin Penetration [PDF]
Actinic keratosis and cutaneous squamous cell carcinoma are of increasing importance with aging and increased ultraviolet light exposure in Western societies. Efficient and well-tolerated therapy is still a matter of concern.
Korting, Hans Christian +3 more
core +1 more source
Intense pustular reaction during treatment of actinic keratosis with ingenol mebutate [PDF]
Introduction. Actinic keratosis is a common diagnosis in dermatological practice. Lesions usually appear on senile skin or skin exposed to sunlight. As they can progress to squamous cell carcinoma, all lesions should be properly treated.
Dorota Jaśkiewicz-Nyckowska +2 more
core +1 more source
Defining the actinic keratosis field: a literature review and discussion [PDF]
Despite the chronic and increasingly prevalent nature of actinic keratosis (AK) and existing evidence supporting assessment of the entire cancerization field during clinical management, a standardized definition of the AK field to aid in the ...
I. Figueras Nart +25 more
core +1 more source
Pharmacological treatment of actinic keratosis
Actinic keratosis (AK) is a disease characterized by hyperkeratotic lesions on skin damaged by ultraviolet. radiation. These lesions may progress to squamous cell or basal cell carcinoma.
Ewa Zwierzyńska +2 more
core +1 more source
Efficacy of imiquimod 3.75% from Lmax according to the number of actinic keratosis lesions
Imiquimod 3.75% reduces 92.2% of all actinic keratosis (AK) lesions, assumed to include both subclinical and clinical lesions, across a large sun-exposed field such as the full face or balding ...
Peris, Ketty
core +1 more source
Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan +8 more
wiley +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
The role of analysis of EVER2 haplotypes in actinic keratosis
Introduction . Polymorphisms of EVER genes are related to increased risk of actinic keratosis (AK), squamous skin cancers (SCC) and cervical cancer. Objective . The aim of this study was to analyze the haplotypes of the EVER 2 gene in 65 subjects
Magdalena Malejczyk +4 more
core +1 more source

