Results 61 to 70 of about 9,440 (219)

Cutaneous photosensitivity of phototheranostic porphyrin–lipid nanoparticles

Photochemistry and Photobiology, EarlyView.
Porphyrin‐lipid nanoparticles (PORPHYSOMES) exhibit significantly less severe and shorter‐lasting skin photosensitivity to sunlight compared to a therapeutically equivalent dose of porfimer sodium (PHOTOFRIN) in a rat skin model. The difference was due to altered intradermal distribution and faster clearance of PORPHYSOMES from skin after intravenous ...
Michael S. Valic, Mark Zheng, Theo Husby, Keegan Guidolin, Axel Sahovaler, Sharon Tzelnick, Wenlei Jiang, Michael Halim, Pamela Schimmer, Abdullah El‐Sayes, Chris J. Zhang, Tina Ye, Ivan Kosik, Jason L. Townson, Kenneth K. Ng, Lili Ding, Juan Chen, Jonathan C. Irish, Robert Weersink, Brian C. Wilson, Gang Zheng   +20 more
wiley   +1 more source

Immunomodulatory effects of photodynamic therapy for skin cancer: Potential strategies to improve treatment efficacy and tolerability

Photochemistry and Photobiology, EarlyView.
Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio, Sanjay Anand, Jeffrey B. Travers, Edward V. Maytin, Craig A. Rohan   +4 more
wiley   +1 more source

Contemporary management of actinic keratosis

Journal of Dermatological Treatment, 2019
Actinic keratosis (AK) is a skin lesion characterized by itraepithelial keratinocyte dysplasia and molecular alterations shared with normal chronically sun-damaged skin and squamous cell carcinoma (SCC). AK can undergo spontaneous regression, stable existence, or malignant transformation to cutaneous SCC with progression rates to SCC ranging from 0% to
Michael A. Marchetti, Cristian Navarrete-Dechent, Cristian Navarrete-Dechent, Ashfaq A. Marghoob   +3 more
openaire   +4 more sources

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, EarlyView.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

German S3 guideline “actinic keratosis and cutaneous squamous cell carcinoma” – Long version of the update 2023

EJC Skin Cancer, 2023
Actinic keratosis (AK) are common lesions in light-skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC).
Ulrike Leiter, Markus V. Heppt, Theresa Steeb, Mareike Alter, Teresa Amaral, Andrea Bauer, Falk G. Bechara, Jürgen C. Becker, Eckhard W. Breitbart, Helmut Breuninger, Thomas Diepgen, Thomas Dirschka, Thomas Eigentler, A.K. Stephan El Gammal, Moritz Felcht, Michael J. Flaig, Markus Follmann, Klaus Fritz, Stephan Grabbe, Rüdiger Greinert, Ralf Gutzmer, Axel Hauschild, Uwe Hillen, Stephan Ihrler, Swen Malte John, Lukas Kofler, Oliver Koelbl, Albrecht Krause-Bergmann, Klaus Kraywinkel, Steffen Krohn, Thomas Langer, Carmen Loquai, Christoph R. Löser, Peter Mohr, Dorothée Nashan, Monika Nothacker, Christina Pfannenberg, Carmen Salavastru, Lutz Schmitz, Eggert Stockfleth, Rolf-Markus Szeimies, Claas Ulrich, Susanne Voelter-Mahlknecht, Dirk Vordermark, Michael Weichenthal, Julia Welzel, Kai Wermker, Susanne Wiegand, Claus Garbe, Carola Berking   +49 more
doaj  

Advances of Microneedles for Cancer Diagnosis and Therapy

MedComm – Biomaterials and Applications, Volume 4, Issue 3, September 2025.
Schematic diagram of microneedle for cancer diagnosis and treatment. ABSTRACT As the global incidence of cancer continues to rise, the need for innovative and precisive alternatives to conventional diagnostic and therapeutic methods has become increasingly urgent.
Chunli Yang, Li Zhang, Siyi Wang, Angxi Zhou, Run Tian, Maya Xiang, Ya Ren, Yang Yu, Rong Li, Maling Gou   +9 more
wiley   +1 more source

Spectral Transmittance Analysis of Different Sunscreens Used in Daylight Photodynamic Therapy

Photodermatology, Photoimmunology &Photomedicine, Volume 41, Issue 5, September 2025.
ABSTRACT Introduction The protocol for daylight photodynamic therapy (DL‐PDT) includes the application of sunscreen with an SPF > 30 to block UV radiation and prevent sunburn during the 2 h of exposure to sunlight. Inorganic filters such as titanium dioxide and zinc oxide are not recommended, as they block the visible light needed to activate the ...
Tamara Gracia‐Cazaña, Ana Sánchez‐Cano, Justiniano Aporta, Yolanda Gilaberte   +3 more
wiley   +1 more source

Expressão de marcadores de proliferação celular e apoptose no carcinoma espinocelular de pele e ceratose actínica Expression of cell proliferation and apoptosis biomarkers in skin spinocellular carcinoma and actinic keratose

Anais Brasileiros de Dermatologia, 2009
FUNDAMENTOS: O câncer de pele é o mais frequente tipo de câncer humano e mostra aumento de sua incidência. Em muitos casos, antes do surgimento do carcinoma, instala-se uma lesão precursora, ceratose actínica, podendo evoluir para carcinoma espinocelular.
Marilho Tadeu Dornelas, Michele Fernandes Rodrigues, Dequitier Carvalho Machado, Ângela Maria Gollner, Ana Paula Ferreira   +4 more
doaj   +1 more source

Effects of Secukinumab on Enthesiophyte and Erosion Progression in Psoriatic Arthritis: A One‐Year Double‐Blind, Randomized, Placebo‐Controlled Trial Using High‐Resolution Peripheral Quantitative Computed Tomography

Arthritis &Rheumatology, Volume 77, Issue 8, Page 1015-1025, August 2025.
Objective This study aimed to ascertain the effect of secukinumab on erosion and enthesiophyte progression in psoriatic arthritis (PsA) by using high‐resolution peripheral quantitative computed tomography (HR‐pQCT). Methods This was a phase 4, double‐blind, randomized, placebo‐controlled trial.
Yingzhao Jin, Isaac T. Cheng, Ho So, Billy T. Lai, Shirley K. Ying, Kitty Y. Kwok, James Griffith, Vivian Hung, Cheuk‐Chun Szeto, Jack J. Lee, Ling Qin, Lai‐Shan Tam   +11 more
wiley   +1 more source

Treatment considerations in actinic keratosis [PDF]

Journal of the European Academy of Dermatology and Venereology, 2017
AbstractThe chronic skin condition actinic keratosis (AK) is characterized by the formation of keratotic lesions of variable thickness that are poorly delimited. AK occurs on areas of the skin that have had long‐term exposure to the sun or UV radiation.
openaire   +3 more sources