Results 61 to 70 of about 8,063 (175)

Identification of differentially expressed genes in actinic keratosis samples treated with ingenol mebutate gel.

PLoS ONE, 2020
Actinic keratosis is a common skin disease that may progress to invasive squamous cell carcinoma if left untreated. Ingenol mebutate has demonstrated efficacy in field treatment of actinic keratosis.
Sonia Segura, Alejandra Gadea, Lara Nonell, Evelyn Andrades, Silvia Sánchez, Ramon Pujol, Inmaculada Hernández-Muñoz, Agustí Toll   +7 more
doaj   +1 more source

Blue Light Aminolevulinic Acid Photodynamic Therapy Did Not Induce Detectable CPD or 6–4PP Photolesions in Human Dermal Fibroblasts

Journal of Biophotonics, Volume 19, Issue 8, August 2026.
This study demonstrates that combination BL and 5‐ALA PDT does not induce detectable levels of CPD or 6–4PP photolesions in human dermal fibroblasts in vitro. Our findings contribute to the lesion‐specific genotoxic safety profile of blue light photodynamic therapy, an established research topic.ABSTRACTPhotodynamic therapy (PDT) is an established ...
Julia Stolyar, Evan Austin, Olumide M. Arigbede, Jared Jagdeo   +3 more
wiley   +1 more source

Neutrophil Extracellular Traps Exacerbate UVB‐Induced Photodamage in HaCaT Cells and Mouse Skin via CCDC25/MAPK Pathway

Aging Cell, Volume 25, Issue 8, August 2026.
Neutrophil extracellular traps (NETs) play a pivotal role in UVB‐induced skin photodamage. Mechanistically, NETs bind to the CCDC25 receptor on keratinocytes and subsequently activate the intracellular p‐JNK/JNK signaling pathway, thereby exacerbating skin photodamage.
Yang Zou, Junzhi Li, Yuting Peng, Rui Hu, Ruolin Li, Aijun Chen   +5 more
wiley   +1 more source

Skin lesion triage in organ transplant recipients using line‐field confocal optical coherence tomography: a retrospective classification study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page 1063-1068, August 2026.
Summary Background/objectives: Organ transplant recipients (OTRs) face an elevated risk of keratinocyte carcinomas (KC), leading to a lower threshold for biopsy. Line‐field confocal optical coherence tomography (LC‐OCT) is a non‐invasive imaging technique capable of visualizing malignant skin changes, yet its role in the management of OTRs remains ...
Kevin Jacobsen, Vinzent Kevin Ortner, Stine Regin Wiegell, Peter Alshede Philipsen, Merete Haedersdal   +4 more
wiley   +1 more source

Pharmacy‐based triage to preselect high‐risk individuals for skin cancer screening: A pilot study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
An Buckinx, Laurence Feldmeyer, Philippa Golling, Carlo Mainetti, Cristina Mangas, Anja Wysocki, Véronique Del Marmol, Regina von Burg, Eva von Wartburg, Stephen P. Jenkinson, Daniel Hohl, Olivier Gaide   +11 more
wiley   +1 more source

Triage von Hautläsionen bei Organtransplantationsempfängern mittels Line‐field Confocal Optical Coherence Tomography: Eine retrospektive Klassifizierungsstudie

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page 1063-1069, August 2026.
Zusammenfassung Hintergrund/Ziele: Empfänger von Organtransplantaten (OTRs) haben ein erhöhtes Risiko für Keratinozytenkarzinome (KC). Dies führt zu einer niedrigeren Schwelle für Biopsien. Die Line‐field Confocal Optical Coherence Tomography (LC‐OCT) ist eine nicht‐invasive Bildgebungstechnik, mit der maligne Hautveränderungen sichtbar gemacht werden ...
Kevin Jacobsen, Vinzent Kevin Ortner, Stine Regin Wiegell, Peter Alshede Philipsen, Merete Haedersdal   +4 more
wiley   +1 more source

Assessing the Dermal Epidermal Junction of Hyperkeratotic Actinic Keratoses via Line‐Field Confocal Optical Coherence Tomography

International Journal of Dermatology, Volume 65, Issue 8, Page 1676-1680, August 2026.
Actinic keratoses (AK) are ultraviolet (UV)‐correlated precursor lesions of invasive cutaneous squamous cell carcinoma (iSCC). AK thickness does not correlate with increased iSCC transformation, but dermal‐epidermal junction (DEJ) protrusion does. The DEJ of hyperkeratotic lesions is harder to study via line‐field confocal optical coherence tomography (
Simone Michelini, Pietro Scribani Rossi, Giuseppe Gemma, Flavia Persechino, Giordano Vespasiani, Claudio Conforti, Francesco Ricci, Carmen Cantisani, Giovanni Pellacani   +8 more
wiley   +1 more source

Expressão de marcadores de proliferação celular e apoptose no carcinoma espinocelular de pele e ceratose actínica Expression of cell proliferation and apoptosis biomarkers in skin spinocellular carcinoma and actinic keratose

Anais Brasileiros de Dermatologia, 2009
FUNDAMENTOS: O câncer de pele é o mais frequente tipo de câncer humano e mostra aumento de sua incidência. Em muitos casos, antes do surgimento do carcinoma, instala-se uma lesão precursora, ceratose actínica, podendo evoluir para carcinoma espinocelular.
Marilho Tadeu Dornelas, Michele Fernandes Rodrigues, Dequitier Carvalho Machado, Ângela Maria Gollner, Ana Paula Ferreira   +4 more
doaj   +1 more source

Safe Use of Adrenaline in Cryosurgery for Eyelid Basal Cell Carcinoma Evaluated With Infrared Thermography

International Wound Journal, Volume 23, Issue 8, August 2026.
ABSTRACT The efficacy of cryosurgery for skin cancers is believed to depend on thaw time, which may be influenced by the presence of adrenaline in local anaesthetics due to its vasoconstrictive effects. This is the first study to perform detailed, non‐invasive temperature measurements using infrared (IR) thermography during cryosurgery for basal cell ...
Anna H. C. Wiktorin, Bohman Elin, Johanna V. Berggren, John Albinsson, Sheikh Rafi, Malmsjö Malin   +5 more
wiley   +1 more source

RATIONALE, DEVELOPMENT AND IMPLEMENTATION OF THE FUNCTIONAL-ORGANIZATIONAL MODEL FOR IMPROVEMENT OF SECONDARY PREVENTION OF ACTINIC KERATOSIS

Клінічна та профілактична медицина, 2019
It is known that effective prevention of skin cancer is to identify individuals with a high level of risk factors for skin cancer, timely diagnosis and active treatment of precancerous skin lesions.
О. О. Оshyvalova, O. L. Zyukov
doaj   +1 more source