Results 261 to 270 of about 6,465 (327)
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The Lancet Oncology
BACKGROUND Actinium-225 (225Ac) prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) is a novel therapy for metastatic castration-resistant prostate cancer (mCRPC). We aimed to report the safety and antitumour activity of 225Ac-PSMA RLT of
M. Sathekge +26 more
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BACKGROUND Actinium-225 (225Ac) prostate-specific membrane antigen (PSMA) radioligand therapy (RLT) is a novel therapy for metastatic castration-resistant prostate cancer (mCRPC). We aimed to report the safety and antitumour activity of 225Ac-PSMA RLT of
M. Sathekge +26 more
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Journal of Radioanalytical and Nuclear Chemistry, 2004
The first hydrolysis constant (pK1h = 9.4) of Ac3+ cations has been determined using 228Ac radiotracer. The pK1h value of Ac3+is compared to the pK1h values of other Group 3 cations. It is shown that, in contrast to the Group 2, 11, 12 and 13, the heaviest member of the Group 3 Ac3+ hydrolyses at less extent than its lighter homologs.
B. Zielińska, A. Bilewicz
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The first hydrolysis constant (pK1h = 9.4) of Ac3+ cations has been determined using 228Ac radiotracer. The pK1h value of Ac3+is compared to the pK1h values of other Group 3 cations. It is shown that, in contrast to the Group 2, 11, 12 and 13, the heaviest member of the Group 3 Ac3+ hydrolyses at less extent than its lighter homologs.
B. Zielińska, A. Bilewicz
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Chemical Biology and Drug Design, 2023
In nuclear medicine, cancers that cannot be cured or can only be treated partially by traditional techniques like surgery or chemotherapy are killed by ionizing radiation as a form of therapeutic treatment.
Maria Hassan +4 more
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In nuclear medicine, cancers that cannot be cured or can only be treated partially by traditional techniques like surgery or chemotherapy are killed by ionizing radiation as a form of therapeutic treatment.
Maria Hassan +4 more
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Generator of Actinium-228 and a Study of the Sorption of Actinium by Carbon Nanomaterials
Radiochemistry, 2020A method has been developed for isolation of 228Ac from aged samples of natural 232Th. Macroscopic amounts of the thorium bulk (20 g) were separated by its extraction by a solution of di(2-ethylhexyl)phosphoric acid in toluene from 4 M HNO3 solutions, with microamounts of 228Ra and 228Ac remaining in the aqueous phase.
A. G. Kazakov +5 more
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The Metabolism of Actinium in the Rat
Health Physics, 1970AbstractThe distribution and retention of 227Ac in rat tissues has been studied after intravenous injection of the nuclide, in equilibrium with its daughters, as a complex with serum proteins, as nitrate, citrate or DTPA complex.
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Cancer Research
Epidermal growth factor receptor (EGFR) is expressed in approximately 80-85% of colorectal cancer (CRC). While anti-EGFR antibodies benefit some CRC patients, tumors with kirsten rat sarcoma (KRAS) or B-rapidly accelerated fibrosarcoma (BRAF), a proto ...
A. Tikum +11 more
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Epidermal growth factor receptor (EGFR) is expressed in approximately 80-85% of colorectal cancer (CRC). While anti-EGFR antibodies benefit some CRC patients, tumors with kirsten rat sarcoma (KRAS) or B-rapidly accelerated fibrosarcoma (BRAF), a proto ...
A. Tikum +11 more
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The spectrochemistry of actinium
Spectrochimica Acta, 1957Abstract For spectrochemical detection or determination of actinium (89Ac) the wavelengths and estimated relative intensities (100 or greater) of 109 strong lines are presented. The wavelengths range from 2558.08 to 7866.10 A. Thirty-two lines are characteristic of Ac I, 63 belong to Ac II, 7 are assigned to Ac III, 2 possibly to Ac IV, and 5 to Ac0.
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The Journal of Physical Chemistry, 1960
Several 5 to 10 mg samples of Ac/sup 227/ were prepared from purified salts by lithium reduction of actinium fluoride and volatilization of the actinium. Sufficient datu were accumulated to permit calculation of an apprcximate value of the vapor pressure of the element at volatilization temperature.
K. W. Foster, L. G. Fauble
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Several 5 to 10 mg samples of Ac/sup 227/ were prepared from purified salts by lithium reduction of actinium fluoride and volatilization of the actinium. Sufficient datu were accumulated to permit calculation of an apprcximate value of the vapor pressure of the element at volatilization temperature.
K. W. Foster, L. G. Fauble
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Journal of Instrumentation
Actinium-225 (Ac-225) is a promising alpha emitter for radionuclide therapy due to its remarkable clinical efficacy in treating prostate cancer. The daughter radionuclides of Ac-225 emit beta particles with energies exceeding the Cherenkov-light ...
S. Yamamoto +6 more
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Actinium-225 (Ac-225) is a promising alpha emitter for radionuclide therapy due to its remarkable clinical efficacy in treating prostate cancer. The daughter radionuclides of Ac-225 emit beta particles with energies exceeding the Cherenkov-light ...
S. Yamamoto +6 more
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Isis, 1971
(OMING AS IT DID in the midst of the excitement over X rays, Henri Becquerel's s-1896 discovery of radioactivity attracted little attention from physicists.1 Chemists were even less interested: radiation, after all, was the province of the physicists and there seemed little in Becquerel's rays that might prove rewarding to a chemist.
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(OMING AS IT DID in the midst of the excitement over X rays, Henri Becquerel's s-1896 discovery of radioactivity attracted little attention from physicists.1 Chemists were even less interested: radiation, after all, was the province of the physicists and there seemed little in Becquerel's rays that might prove rewarding to a chemist.
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