Results 71 to 80 of about 821,587 (214)

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, Volume 13, Issue 50, 7 September 2026.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Impact of Regional Hepatic Immunosuppression With Budesonide on Bacterial Elimination in Porcine Abdominal Sepsis

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 8, September 2026.
ABSTRACT Introduction The liver is essential for bacterial elimination, preventing intestinal bacteria from entering the systemic circulation, and for producing inflammatory cytokines. Glucocorticoids have been reported to exert heterogeneous effects on bacterial clearance in sepsis.
Katja Hanslin, Paul Skorup, Frida Wilske, Anders Larsson, Eva Tano, Jan Sjölin, Miklos Lipcsey   +6 more
wiley   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, Volume 40, Issue 16, August 2026.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source

Oral Microbial and Metabolic Alterations in Patients With Oral Lichen Planus Concomitant With Type 2 Diabetes Mellitus

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
We conducted a cross‐sectional study involving three groups: OLP‐DM, OLP, and healthy controls. Salivary 16S rRNA sequencing and untargeted metabolomics revealed distinct microbial and metabolic profiles among groups, which were associated with disease severity.
Xiaomeng Ren, Kaiyi Li, Xiaowen Kong, Jiawen Li, Hong Hua, Chunlei Li   +5 more
wiley   +1 more source

Actinobacillus actinomycetemcomitans induction of apoptosis in infected macrophages [PDF]

, 1995
P(論文)The gram-negative periodontopathic bacteria Actinobacillus actinomycetemcomitans causes juvenile periodontitis. In the present study, A. actinomycetemcomitans was shown to be cytotoxic to J774A.1 cells, a monocyte-macrophage cell line, and to murine
24420, 加藤, 幸紀
core  

Unusual presentation of osteomyelitis of the tuber calcanei in a 16‐month‐old gelding

Equine Veterinary Education, Volume 38, Issue 8, Page e480-e487, August 2026.
Summary A 16‐month‐old Morgan gelding was referred for evaluation of a right hindlimb lameness (grade 4/5, AAEP) accompanied by swelling of the right calcaneal region. Clinical signs had been present for approximately 4 weeks prior to referral.
A. M. Arreola, C. Serna, K. G. Mitchell, A. Merchán   +3 more
wiley   +1 more source

Novel Experimental Mouse Model to Study the Pathogenesis and Therapy of Actinobacillus pleuropneumoniae Infection

Pathogens
Actinobacillus pleuropneumoniae (APP) is a major cause of lung infections in pigs. An experimental mouse has the edge over pigs pertaining to the ease of experimental operation, disease study and therapy, abundance of genetic resources, and cost. However,
Duc-Thang Bui, Yi-San Lee, Tien-Fen Kuo, Zeng-Weng Chen, Wen-Chin Yang   +4 more
doaj   +1 more source

Porphyromonas gingivalis Outer Membrane Vesicles‐Associated DNA Triggers Inflammation by Inducing IL‐6 in Astrocytes

Molecular Oral Microbiology, Volume 41, Issue 4, Page 227-238, August 2026.
Pg releases OMVs which contain Pg genomic DNA. The Pg OMVs‐associated DNA is incorporated into astrocytes via endocytosis and increases IL‐6 mRNA expression via TLR9. These effects of Pg OMVs may induce neuroinflammation, which could contribute to the onset and progression of AD in periodontal disease.
Ayu Takai, Kaya Yoshida, Yuka Hiroshima, Ayu Ikuta, Mariko Seyama, Yuta Uemura, Hiromichi Yumoto, Kazumi Ozaki   +7 more
wiley   +1 more source

Application of Microbial and Parasitology Techniques for Diagnosis in Laboratory Rodents

Current Protocols, Volume 6, Issue 7, July 2026.
Abstract Pathogen diagnosis in rodents through effective health monitoring programs is essential for maintaining high welfare and standards in laboratory animal facilities. Although many animal facilities are increasingly adopting real‐time polymerase chain reaction testing of environmental or filter samples for pathogen detection, thereby reducing the
Debora Rapaport, Maya Levin Arama, Michael Harlev   +2 more
wiley   +1 more source

Herd-level risk factors for chronic pleurisy in finishing pigs: a case-control study

Porcine Health Management, 2020
Background Chronic pleurisy is a common finding in slaughtered pigs in post-mortem meat inspection. The prevalence of pleurisy has been increasing during the last decade also in Finland.
Outi Hälli, Minna Haimi-Hakala, Claudio Oliviero, Mari Heinonen   +3 more
doaj   +1 more source