Results 41 to 50 of about 24,624 (208)

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

open access: yesiMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni   +26 more
wiley   +1 more source

Actinomyces in Tonsillectomy Materials

open access: yesActa Medica Alanya, 2020
Aim: Tonsillectomy is one of the most common surgeries in the pediatric age group. Actinomyces species are Gram-positive, non-spore-forming facultative anaerobic bacteria.
Özlem Ceren Güni̇zi̇   +1 more
doaj   +1 more source

Ordered assembly of Cas12a for better performance of CRISPR/Cas system with application to the diagnosis of dental caries

open access: yesInterdisciplinary Medicine, EarlyView.
Here, we present a tetrahedral DNA framework (TDF)‐mediated Cas12a ordered assembly strategy. TDFs arrange CRISPR/Cas12a into ordered structures controllably, enhancing catalytic efficiency through localized Cas12a hotspots while maintaining spatial intervals to facilitate substrate diffusion.
Yining Zhao   +6 more
wiley   +1 more source

Nasal Actinomyces in a 7-year-old Boy with Recurrent Nasal Bleeding: A Case Report

open access: yesJournal of Pediatric Research, 2022
Actinomyces rarely cause infections in nasal sinuses with local symptoms and its identification is difficult so the initiation of treatment might be delayed. A 7-year-old boy with recurrent nasal bleeding was found to be infected in the paranasal sinuses
Mohammad Solduzian   +3 more
doaj   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari   +3 more
wiley   +1 more source

Long-Term Follow-up Results of Primary Canaliculitis Patients

open access: yesTürk Oftalmoloji Dergisi, 2023
Objectives:To evaluate the demographic characteristics, clinical presentation, microbiologic profile, and treatment results of patients with primary canaliculitis.Materials and Methods:Patients diagnosed and treated for primary canaliculitis between May ...
Emine Gökçen Bayuk   +4 more
doaj   +1 more source

Organ‐Specific Human Microbiomes and Dysbiosis: Mechanistic Links to Disease and Emerging Therapeutic Strategies

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Schematic overview of the human microbiome and major microbiota‐derived metabolites across body sites, highlighting the gut–brain, gut–heart, and gut–kidney axes in host physiology and disease. ABSTRACT Background The human microbiome is a dynamic and diverse community of microorganisms that affects susceptibility to illness and promotes wellness ...
Awadh Alanazi
wiley   +1 more source

Premature labor and neonatal sepsis caused by Actinomyces neuii

open access: yesJournal of Infection and Public Health, 2019
Actinomycosis is a rare infection in patients younger than 10 years of age. It mainly affects the cervicofacial region, but many other sites of infection have been recognized.
Fahad Alsohime   +5 more
doaj   +1 more source

Zinc‐stabilized stannous fluoride modulates the periodontal microbiome, reducing Fusobacteria, key Gram‐negative species, and overall inflammation within an experimental gingivitis clinical trial

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the effects of a dentifrice containing stannous fluoride stabilized with zinc phosphate on subgingival microbiome composition and clinical inflammation during experimental gingivitis, compared with a sodium fluoride control. Methods This investigation was conducted as a secondary analysis of a randomized,
Kristopher A. Kerns   +8 more
wiley   +1 more source

Pulmonary Actinomycosis in a 65-Year-Old Female with Poor Oral Dentition

open access: yesDiagnostics
Pulmonary actinomycosis is an uncommon clinical entity that can be challenging to diagnose due to its non-specific symptomatology. Misdiagnosis and delayed treatment may result in invasive procedures and extended antimicrobial treatment courses.
Sha Yi   +5 more
doaj   +1 more source

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