Results 51 to 60 of about 1,716 (133)

Advancements and Challenges in Salivary Metabolomics for Early Detection and Monitoring of Systemic Diseases

MedComm, Volume 6, Issue 10, October 2025.
Salivary metabolomics offers a noninvasive and effective approach for early disease detection and monitoring. Salivary metabolites reflect systemic metabolism, inflammation, and external factors such as diet and stress. Advance in bioinformatics and machine learning facilitates the identification of metabolic biomarkers with high diagnostic accuracy ...
Xinyuan Zhao, Xu Chen, Zihao Zhou, Jiarong Zheng, Yunfan Lin, Yucheng Zheng, Rongwei Xu, Shen Hu, Li Cui   +8 more
wiley   +1 more source

Altered gut microbiota and short chain fatty acids in Chinese children with autism spectrum disorder

Scientific Reports, 2019
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is characterized by impairments in social interactions and communication, restricted interests and repetitive behaviors. Several studies report a high prevalence of gastrointestinal (GI)
Simeng Liu, Enyao Li, Zhenyu Sun, Dongjun Fu, Guiqin Duan, Miaomiao Jiang, Yong Yu, Lu Mei, Pingchang Yang, Youcai Tang, Pengyuan Zheng   +10 more
doaj   +1 more source

From Sea to Soil: Marine Actinobacteria in Integrated Seawater Energy Agriculture Systems (ma‐ISEAS)

GCB Bioenergy, Volume 17, Issue 9, September 2025.
Conventional ISEAS vs. ma‐ISEAS. The innovation involves using native marine free‐living and endophytic plant growth‐promoting actinobacteria (PGPA) to enhance Salicornia and mangrove productivity. Key modifications are highlighted in red across stages I–VI, showcasing the improved sustainability and efficiency of ma‐ISEAS.
Synan F. AbuQamar, Khaled A. El‐Tarabily   +1 more
wiley   +1 more source

A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome

Communications Biology
The nasal cavity harbors diverse microbiota that contributes to human health and respiratory diseases. However, whether and to what extent the host genome shapes the nasal microbiome remains largely unknown. Here, by dissecting the human genome and nasal
Xiaomin Liu, Xin Tong, Leying Zou, Yanmei Ju, Mingliang Liu, Mo Han, Haorong Lu, Huanming Yang, Jian Wang, Yang Zong, Weibin Liu, Xun Xu, Xin Jin, Liang Xiao, Huijue Jia, Ruijin Guo, Tao Zhang   +16 more
doaj   +1 more source

Unveiling the Relationship Between Oral Microbiota and Alzheimer's Disease: A Genetic Instrumental Variable Analysis via Mendelian Randomization

Brain and Behavior, Volume 15, Issue 8, August 2025.
This study investigated the association between oral microbiota (OM) and Alzheimer's disease (AD). The causal relationship between OM and AD was established using Mendelian randomization (MR) methods and further supported by gene function analyses. ABSTRACT Background: The potential relationship between oral microbiota (OM) and Alzheimer's disease (AD)
Zhichao Li, Yihan Kang, Shuai Li, Shiqi Guo, Hui Zheng   +4 more
wiley   +1 more source

Sputum Microbiota Compositions Correlate With Metabolome and Clinical Outcomes of COPD‐Bronchiectasis Association: A Prospective Cohort Study

Exploration, Volume 5, Issue 4, August 2025.
This study aimed to determine how microbiota compositions (via 16S rRNA sequencing) correlate with clinical outcome and metabolome (via liquid chromatography/mass spectrometry) of CBA. Sputum microbiome and metabolome profiles of CBA were well separated from COPD but not bronchiectasis, partly driven by the higher abundance of Proteobacteria in CBA ...
Zhen‐feng He, Xiao‐xian Zhang, Cui‐xia Pan, Xin‐zhu Yi, Yan Huang, Chun‐lan Chen, Shan‐shan Zha, Lai‐jian Cen, Han‐qin Cai, Lei Yang, Jia‐qi Gao, Hui‐min Li, Zhen‐hong Lin, Sheng‐zhu Lin, Zhang Wang, Nan‐shan Zhong, Wei‐jie Guan   +16 more
wiley   +1 more source

Bridging lab and industry: The impact of a bio‐conversion unit on black soldier fly larvae production and microbiome dynamics

JSFA reports, Volume 5, Issue 7, Page 304-314, July 2025.
Abstract Background This study evaluates the viability of a novel bio‐conversion unit (BCU) for extensive black soldier fly larvae (BSFL) production as a sustainable feed additive for livestock. The BCU's effectiveness in converting organic byproducts into valuable biomass via the production of BSFL was assessed to reduce reliance on environmentally ...
William J. S. Edwards, Chloe Skingle, Richard Small, Robert Barker, Anastasios D. Tsaousis   +4 more
wiley   +1 more source

Impact of gut microbiota on nonalcoholic fatty liver disease: insights from a leave-one-out cross-validation study

Frontiers in Microbiology
IntroductionEnteric dysbacteriosis is strongly associated with nonalcoholic fatty liver disease (NAFLD). However, the underlying causal relationship remains unknown. Thus, the present study aimed to investigate the relationship between gut microbiota and
Tongtong Pan, Lihuang Su, Yiying Zhang, Fangfang Yi, Yongping Chen   +4 more
doaj   +1 more source

Exploring the Gut and Oral Microbiomes in Psychoactive Substance Use: A Scoping Review of Clinical Studies

Journal of Neurochemistry, Volume 169, Issue 7, July 2025.
Substance use disorders are linked to high treatment dropout rates and limited therapeutic options. Clinical studies show that substance use disrupts gut and oral microbiomes, decreasing beneficial bacteria and increasing proinflammatory and opportunistic microbes.
Artūras Barkus, Vaida Baltrūnienė, Lina Barkienė, Justė Baušienė, Tomas Baltrūnas, Marius Brazys, Kornelija Rauduvytė, Paulina Kazlauskaitė, Augustinas Baušys   +8 more
wiley   +1 more source

Moderate Dietary Protein Restriction Optimized Gut Microbiota and Mucosal Barrier in Growing Pig Model

Frontiers in Cellular and Infection Microbiology, 2018
Appropriate protein concentration is essential for animal at certain stage. This study evaluated the effects of different percentages of dietary protein restriction on intestinal health of growing pigs. Eighteen barrows were randomly assigned to a normal
Xiyue Chen, Peixia Song, Peixin Fan, Ting He, Devin Jacobs, Crystal L. Levesque, Lee J. Johnston, Linbao Ji, Ning Ma, Yiqiang Chen, Jie Zhang, Jinshan Zhao, Xi Ma, Xi Ma, Xi Ma   +14 more
doaj   +1 more source