Results 81 to 90 of about 22,661 (198)

Actinomycin Analogs From Streptomyces polyantibioticus S4D258: Structural Elucidation and Antiproliferative Activity Against Triple‐Negative Breast Cancer

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Fifteen new actinomycin analogs, named actinomycins H1–H15, are identified from S. polyantibioticus S4D258. Actinomycins H7–H15 are truncated actinomycin analogs. Actinomycins H1–H6 and H9 exhibit significant antiproliferative activities against both MDA‐MB‐231 and 4T1 TNBC cells.
He Pang, Xiao‐Min Huang, Usama Ramadan Abdelmohsen, Li Shen, Jun Wu   +4 more
wiley   +1 more source

Isolation and Characterization of Antibiotic Producing Actinomycetes from Soils of Hawassa, Southern Ethiopia

East African Journal of Biophysical and Computational Sciences
Antimicrobial resistance has increased drastically in recent years in developing countries, and it has leading public health concern. With almost all organisms becoming multidrug-resistant to the commonly used antibiotics, there is a need to search for ...
Alazar Keshamo, Abayneh Agena, Zufan Bedewi   +2 more
doaj   +1 more source

Total Synthesis of Chaxalactin B, a Rare 22‐Membered Macrolactone

ChemistryEurope, Volume 4, Issue 10, October 2026.
The first total synthesis of the antibacterial 22‐membered macrolactone chaxalactin B has been accomplished in 23 steps (longest linear sequence). Key transformations feature a stereoselective Marshall propargylation, a Suzuki–Miyaura coupling for the assembly of the main C1–C9 and C10–C25 fragments, and a late‐stage Shiina macrolactonization ...
Ophélie Montiège, Thomas Defuentes, Axelle Berrou, Charlotte Boullier, Frédéric Legros, Catherine Gaulon‐Nourry, Anne‐Sophie Castanet, Anne‐Caroline Chany   +7 more
wiley   +1 more source

From Rhizosphere to Resistance: Microbe‐Plant Interactions in Eco‐Smart Biocontrol

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Conceptual framework of eco‐smart biocontrol: Root exudates released by plants shape rhizosphere microbial community assembly by selectively recruiting beneficial microorganisms. These microbes suppress phytopathogens through direct mechanisms such as antibiosis, parasitism, enzyme production, and niche competition, while simultaneously activating ...
Shilpy Singh, Varun Kumar Sharma, Dharmsheel Shrivastav, Jayant M. Kushwaha, Manoj Kumar Mishra, Mirza Masroor Ali Beg   +5 more
wiley   +1 more source

Two distinct alcohol dehydrogenase classes mediate bacterial 2‐hydroxyethylphosphonate catabolism

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Phosphonates are molecules containing a direct carbon‐phosphorus bond. In nature, these compounds are produced by a variety of organisms, and many environmental microbes are able to degrade specific phosphonates and feed on them. This work focuses on 2‐hydroxyethylphosphonate (HEP)—a natural compound that is found frequently in the environment,
Francesca Piazza, Marianna Rodella, Nicholas Salanti, Giovanni Merici, Elisa Rossi, Claudio Rivetti, Florian Götzinger, Katharina Pallitsch, Alessio Peracchi   +8 more
wiley   +1 more source

pРНК-гены актиномицетов, гомологичные генам pРНК-кластера Streptomyces globisporus 1912-2

Фактори експериментальної еволюції організмів, 2014
Aims. To study the spread of the rRNA-genes homologous fо analogous genes of S. globisporus 1912-2 in the genomes of actinomycetes. Methods. The program BLASTN 2.2.29 was used for in silico analysis of Internet base of dates NCBI (Microbial genomes ...
Л. В. Полищук, Б. П. Мацелюх   +1 more
doaj  

Patterns of Functional Redundancy and Anaerobic Metabolic Potential Characterise the Skin Microbiome of a Critically Endangered Sawfish

Environmental Microbiology, Volume 28, Issue 10, October 2026.
The largetooth sawfish skin supports a distinct microbiome enriched in anaerobic metabolic and dormancy potential, consistent with microbial persistence under low‐oxygen conditions. Greater among‐individual taxonomic variability coupled with functional redundancy potential supports a lottery‐like mechanism of microbiome assembly.
Michael P. Doane, Belinda Martin, Emma Kerr, Elizabeth A. Dinsdale, Malak Malak Rangers, Leonardo Guida, Pete M. Kyne   +6 more
wiley   +1 more source

Core and Keystone Epiphytic and Endophytic Bacteria Associated With Potato Leaves Are Driven by Cultivar and Site

Environmental Microbiology, Volume 28, Issue 10, October 2026.
Potato leaf bacterial communities across Australian potato‐growing sites varied by cultivar and site, with endophytes more strongly influenced by cultivar than epiphytes. Delftia sp. was the core endophyte and the only putative keystone taxon in both endophyte and epiphyte communities, and Pantoea sp. was the only core epiphyte.
Sumitra Saha, Anish S. Shah, Treena I. Burgess, Kirsty L. Bayliss   +3 more
wiley   +1 more source

Development and validation of a challenge model using geosmin‐spiked feeds to obtain off‐flavor compounds in tissues of Atlantic salmon, Salmo salar

Journal of the World Aquaculture Society, Volume 57, Issue 5, October 2026.
Abstract Fish produced within recirculating aquaculture systems may develop flavors not desired by end‐consumers, hereafter “off‐flavor,” which is largely attributed to geosmin accumulation in fish tissues. To develop methods for mitigating geosmin accumulation, a reliable and reproducible method of introducing geosmin in fish tissue is needed. Current
Mariah Pearson, Robert Harrington, Gail Schwieterman, Matt Hawkyard   +3 more
wiley   +1 more source

Actinomycetes studies in Tunisia

Research in Microbiology
Tunisia, located in North Africa, has a diverse topography along the Mediterranean Sea to the Sahara Desert. These environments encompass oases, rhizosphere soils, desert deposits, saline wetlands, offshore oilrigs, and ancient monument rocks. The country's varied environments have led to the isolation of a multitude of actinomycetes.
Souleima Dhahbi, Jeonghee Lee, Dohee Ryu, Ganiyu Akinniyi, Inho Yang   +4 more
openaire   +2 more sources