Results 71 to 80 of about 5,487,280 (257)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Real-Time Prediction of Observed Action Requires Integrity of the Dorsal Premotor Cortex: Evidence From Repetitive Transcranial Magnetic Stimulation

Frontiers in Human Neuroscience, 2018
Studying brain mechanisms underlying the prediction of observed action, the dorsal premotor cortex (PMd) has been suggested a key area. The present study probed this notion using repetitive transcranial magnetic stimulation (rTMS) to test whether ...
Louisa F. M. Brich, Christine Bächle, Joachim Hermsdörfer, Waltraud Stadler   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Effects of action observation on learning non-weight-bearing gait with crutches

Cogent Psychology, 2018
Action observation (AO) has been used to improve rehabilitation outcomes. We examined the effects of AO gait training on the acquisition of a non-weight-bearing (NWB) gait with crutches.
Hiroshi Osaka, Daisuke Fujita, Kenichi Kobara, Yosuke Yoshimura, Tadanobu Suehiro   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking differences in action perception with differences in action execution [PDF]

, 2015
Successful human social interactions depend upon the transmission of verbal and non-verbal signals from one individual to another. Non-verbal social communication is realized through our ability to read and understand information present in other people ...
Kilner, JM, Ricciardi, L, Edwards, MJ, Macerollo, A, Bose, S   +4 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The effects of mirror visual feedback involved network priming on embodiment perception in healthy subjects: a proof-of-concept study

Frontiers in Neuroscience
IntroductionMirror visual feedback (MVF) efficacy varies with individual embodiment perception.ObjectiveThe study aimed to investigate the behavioral effects of priming via the rubber hand illusion (RHI) and action observation (AO) on embodiment ...
Yongxin Luo, Yongxin Luo, Lin Cai, Juan Li, Jianwei Lu, Jianwei Lu, Li Ding   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

EMPOWERMENT IN PARTICIPATORY ACTION RESEARCH CONDUCTED IN MALAYSIA

, 2014
Participatory action research advocates participation and egalitarian relationship among its participants. This study was conducted in Malaysia amongst the Malay society, where the Malay society has been labelled as having high power distance in its ...
Puteh-Behak, Fariza
core   +1 more source