Results 101 to 110 of about 4,571,499 (346)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Light meson physics and scale setting from a mixed action with Wilson twisted mass valence quarks [PDF]

open access: hybrid, 2022
Gregorio Herdoíza   +8 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The Dynamical Emergence of Biology From Physics: Branching Causation via Biomolecules

open access: yesFrontiers in Physiology, 2019
Biology differs fundamentally from the physics that underlies it. This paper1 proposes that the essential difference is that while physics at its fundamental level is Hamiltonian, in biology, once life has come into existence, causation of a contextual ...
George F. R. Ellis, Jonathan Kopel
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

DISCUSION ACERCA DE LA UTILIDAD E IMPORTANCIA DE LOS LABORATATORIOS DE FISICA EN LA ENSEÑANZA ACTUAL [PDF]

open access: yesGondola, 2010
n the process of teaching and learning of physics, are referenced various scenarios in which interaction takes place between actors involved in this process. One of the main sites is the laboratory, this has been vital throughout scientific history.
ARNULFO SEGURA, JEIMY LORENA PEREZ
doaj  

Least Action Principle in Physics

open access: yes, 2018
We learn physics by starting it from classical problem, where Newton's laws govern the classical physics. In high school or often in early physics in undergraduate, we still solve classic problem with newton's equation of motion. In this article, I will show that there's more alternative way to see classical problem instead seeing from Newton's law ...
openaire   +2 more sources

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

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