Results 31 to 40 of about 102,820 (219)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A Probe into the Evolution of Primordial Perturbations in the f(T) Gravity Framework with Chaplygin Gas

open access: yesParticles
This work is focused on studying the cosmology of variable modified Chaplygin gas (VMCG) in the framework of exponential and logarithmic f(T) theory. The equation of state (EoS) for VMCG in exponential and logarithmic f(T) gravity shows quintom behavior.
Sanjeeda Sultana   +2 more
doaj   +1 more source

Principles of Least Action in Urban Traffic Flow

open access: yesFindings, 2020
Drawing on the strong connection between traffic modelling and physics we apply the principle of least action to traffic flow in an urban setting.
Willem Klumpenhouwer, Lina Kattan
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Gender gaps and gendered action in a first-year physics laboratory

open access: yesPhysical Review Physics Education Research, 2016
[This paper is part of the Focused Collection on Gender in Physics.] It is established that male students outperform female students on almost all commonly used physics concept inventories.
James Day   +4 more
doaj   +1 more source

Play-Based Physics Learning in Kindergarten

open access: yesEducation Sciences, 2022
This article highlights the importance of play as a learning approach in early physics education. It demonstrates the concept of an innovative didactic method that combines children’s free play with physics learning in kindergarten.
Nathalie Glauser-Abou Ismail   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Exploring Microbial Dynamics and Heat Transmission in a Nonlinear Radiative Maxwell Nanomaterial With Sensitivity Analysis

open access: yesAdvances in Mathematical Physics
In the automotive, electronics, and energy sectors, heat exchangers and cooling systems can be improved by the flow dynamics of thermally enriched nanomaterials across enlarged surfaces. In biomicrosystems, bionanocooling units, and the petroleum sector,
B. M. Jewel Rana   +3 more
doaj   +1 more source

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