Results 41 to 50 of about 93,090 (263)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Voltaire, Maupertuis and the 18th century debate on the principle of least action: scientific and extrascientific features

open access: yesFilosofia Unisinos, 2021
Towards the middle of the 18th century, Pierre-Louis Moreau de Maupertuis proposed the “principle of least action” as a fundamental law of physics and as a proof of the existence of God. Samuel König and other contemporary authors criticized Maupertuis’
Roberto de Andrade Martins   +1 more
doaj  

Penerapan Model Pembelajaran Relating, Experiencing, Applying, Cooperating, Transferring (REACT) untuk Meningkatkan Pemahaman Konsep Fisika SMA

open access: yesPhysics Education Research Journal, 2020
The aims of this study was to test the effectiveness of the Relating, Experiencing, Applying, Cooperating, Transferring (REACT) learning model in improving students' understanding of physics concepts.
Iqbal Sugita   +4 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Using representational gesture to enact instants in collaborative problem solving in physics

open access: yesPhysical Review Physics Education Research
Embodied forms of representation like gesture have been shown to play an important role in how learners conceptualize phenomena in physics; however, we know little about how students use gesture to capture the idea of instantaneity. Drawing on multimodal
Emma Teresa Booth   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Lie Group Statistics and Lie Group Machine Learning Based on Souriau Lie Groups Thermodynamics & Koszul-Souriau-Fisher Metric: New Entropy Definition as Generalized Casimir Invariant Function in Coadjoint Representation

open access: yesEntropy, 2020
In 1969, Jean-Marie Souriau introduced a “Lie Groups Thermodynamics” in Statistical Mechanics in the framework of Geometric Mechanics. This Souriau’s model considers the statistical mechanics of dynamic systems in their “space of evolution” associated to
Frédéric Barbaresco
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Penanaman Karakter Positif Pelajar Melalui Pembahasan Fenomena-Fenomena Fisika dan Pendekatan Analogi (Hasil Kajian Perkulihan Fisika Dasar)

open access: yesJPFT (Jurnal Pendidikan Fisika dan Teknologi), 2017
The discussion results of Fundamental Physics I lecturing, especially the 1st Newton law about movement, law of Lenz, electromagnetic induction, and law of Bernoulli about pressure of flowing fluid show that in the concepts implicitly there is an action ...
Joni Rokhmat
doaj   +1 more source

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