Results 71 to 80 of about 992,317 (219)
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Principles of Least Action in Urban Traffic Flow
Findings, 2020 Drawing on the strong connection between traffic modelling and physics we apply the principle of least action to traffic flow in an urban setting.
Willem Klumpenhouwer, Lina Kattan
doaj +1 more source
Light Monopoles, Electric Vortices and Instantons [PDF]
, 1995 The physics of the bare Seiberg-Witten action, without supersymmetric partners, is considered in the framework of standard Quantum Field Theory. The topological analysis related to the solutions of the Seiberg-Witten equations is performed and the phase ...
't Hooft +13 more
core +2 more sources
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
Indonesian Journal of Science and Mathematics Education, 2019 :Research In this journal aims to find out the increasing students in understanding the conception of physics through the help of media Crocodile Physics programs. The form of research used in this study is Action Research.
Abdi Novianto, Nirva Diana
doaj +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Constraining the UV with the electroweak effective action
Journal of High Energy PhysicsBy considering an arbitrary bare action describing BSM physics, we use the Barvinsky-Vilkovisky resummation to obtain the most general non-local electroweak effective action at second order in the field strength.
Iberê Kuntz, Amanda Malagi
doaj +1 more source
Jurnal PAJAR (Pendidikan dan Pengajaran), 2017 This research is motivated by the lack of physics student learning outcomes on feature highlights feature of wave class XII SMAN 9 Pekanbaru. This study aims to improve the learning outcomes of physics students on feature highlights wave characteristics ...
Gustariani Gustariani
doaj +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source