Results 211 to 220 of about 12,692,953 (333)

A simulation study of the impact of drug-IKr binding mechanisms on biomarkers of proarrhythmic risk reveals a crucial role in reverse use-dependence of action potential duration and a marked influence on the vulnerable window

Julio Gomis-Tena, Fernando Escobar, Lucía Sagarra Romero   +2 more
openalex   +2 more sources

Restitution slope is principally determined by steady-state action potential duration. [PDF]

Cardiovasc Res, 2017
Shattock MJ, Park KC, Yang HY, Lee AWC, Niederer S, MacLeod KT, Winter J.   +6 more
europepmc   +1 more source

Recovering intrinsic conduction velocity and action potential duration from electroanatomic mapping data using curvature

Caroline H. Roney, Gernot Plank, Shohreh Honarbakhsh, Caterina Vidal Horrach, Simone Pezzuto, Edward J. Vigmond   +5 more
openalex   +1 more source

2-Aminoethoxydiphenyl borate prolongs atrial and shortens ventricular action potential duration through modulation of ion channels in the sarcolemma [PDF]

Mathilde R. Rivaud, Fernanda M. Bosada, S C M Van Amersfoort, Cees A. Schumacher, Ranjit Shama, Joris R. de Groot, Arie O. Verkerk, R F M Coronel, Marieke W. Veldkamp   +8 more
openalex   +1 more source

Regulation of cardiac action potential duration by neurotransmitters and co-transmitters

, 2022
Shailesh R. Agarwal, Chase M. Fiore, Kalyanam Shivkumar, Robert D. Harvey   +3 more
openalex   +1 more source

The generative and catalytic powers of creative, expressive arts in action research

, 2014
Being conscious of how we know what we know, and equally conscious that when we come to such an insight that our ways of knowing are not necessarily the same as everyone else’s, are increasingly essential aspects of methodological literacy.
Goff, Susan
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Interventricular Differences in Action Potential Duration Restitution Contribute to Dissimilar Ventricular Rhythms in <i>ex vivo</i> Perfused Hearts. [PDF]

Front Cardiovasc Med, 2019
Handa BS, Lawal S, Wright IJ, Li X, Cabello-García J, Mansfield C, Chowdhury RA, Peters NS, Ng FS.   +8 more
europepmc   +1 more source

SGK1 inhibition normalizes action potential duration in transgenic LQT2 rabbits but not in LQT1, suggesting a novel gene-specific therapeutic approach in long QT syndrome [PDF]

Michelangela Barbieri, J Lourdaour, Nicolò Alerni, Lucilla Giammarino, Saranda Nimani, Lluis Matas, András Horváth, Katja E. Odening   +7 more
openalex   +1 more source

Interpretable machine learning of action potential duration restitution properties in single-cell models of atrial cardiomyocyte

, 2022
Jun-Seop Song, Young-Seon Lee
openalex   +1 more source