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The effect of the duration of the action potential on contraction in the mammalian heart muscle
Pfl�gers Archiv f�r die Gesamte Physiologie des Menschen und der Tiere, 1968A method is described to control the membrane potential in preparations of mammalian myocardium, and to measure tension simultaneously. The following observations are made:
M, Morad, W, Trautwein
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Determinants of action potential duration in neonatal rat ventricle cells
Cardiovascular Research, 1991The aim was to study the currents that determine the action potential duration in ventricular cells from neonatal rats.Microelectrode measurements of action potentials from ventricle strips were compared with action potentials obtained from isolated myocytes with the whole cell patch clamp method in current clamp mode.
B, Fermini, O F, Schanne
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Somal action potential duration differs in identified primary afferents
Neuroscience Letters, 1986In the present study we examined action potentials recorded from somata in the cat L7 and S1 dorsal root ganglia. We found (i) that there is a characteristic spike duration for each receptor type (e.g. Golgi tendon organ, D-hair) and (ii) that, for a given peripheral fiber conduction velocity, somata whose axons supply low-threshold cutaneous receptors
R D, Rose +3 more
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Lithium ions increase action potential duration of mammalian neurons
Brain Research, 1984During Lucifer Yellow staining of mammalian neurons, intracellular recording revealed a prolongation of the action potential that is probably the result of leakage of lithium ions into the intracellular fluid. In experiments on dorsal root ganglion neurons intracellular iontophoresis of lithium ions also broadened the action potential.
M L, Mayer, V, Crunelli, J A, Kemp
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Cardiac action potential duration and calcium regulation in males and females
Biochemical and Biophysical Research Communications, 2009Adult women have longer QT intervals compared with men of a similar age, indicating differences in the speed of repolarisation of the ventricles. We investigate the influences of gender on ventricular electrophysiology and intracellular Ca(2+) regulation of the guinea pig heart.
Sammy A, Mason, Kenneth T, MacLeod
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Electrotonic effects on action potential duration in perfused rat hearts
2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2009Electrotonic interactions in cardiac tissue have been shown previously to modulate dynamical properties of the myocardium such as action potential duration (APD) and action potential duration restitution. A recent computational study indicated that these electrotonic effects may be strongest in small murine hearts.
Richard D, Walton, Olivier, Bernus
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Stability of Cardiac Action Potential Duration under Periodic Pacing
2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005Action potential duration (APD) alternans is believed to be a loss of stability and contributes much to the reentry arrhythmias. The purpose of this study is to analyze the stability conditions for one-dimension model and higher dimension model. These criterions are concluded by linear stability analysis in nonlinear dynamics. They should be useful for
Han, Xiaodong +4 more
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Heterogeneous memory in restitution of action potential duration in pig ventricles
Journal of Electrocardiology, 2010Restitution of action potential duration and memory importantly affect electrical stability in ventricles. Studies have reported heterogeneous restitution among different regions of the ventricles. However, existence of heterogeneity in memory is not as well investigated.Transmembrane potentials were recorded in endocardial and epicardial tissues from ...
Linyuan, Jing +2 more
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The dependence on heart rate of the human ventricular action potential duration
Cardiovascular Research, 1982For the human electrocardiogram, the relationship between QT interval and heart rate was examined in conditions where the heart rate was changed at different rates. The QT interval provides a measure of the ventricular action potential duration. For slow changes of heart rate, elicited by mild exercise, the dependence of QT interval on heart rate ...
Arnold, L. +4 more
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Compound muscle action potential duration in critical illness neuromyopathy
Muscle & Nerve, 2017ABSTRACTIntroductionWe sought to determine the specificity of compound muscle action potential (CMAP) durations and amplitudes in a large critical illness neuromyopathy (CINM) cohort relative to controls with other neuromuscular conditions.MethodsFifty‐eight patients with CINM who had been seen over a 17‐year period were retrospectively studied ...
Christopher L, Kramer +3 more
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