Results 1 to 10 of about 43,223 (162)

Electrocardiographic Imaging of Repolarization Abnormalities [PDF]

Journal of the American Heart Association, 2021
Background Dispersion and gradients in repolarization have been associated with life‐threatening arrhythmias, but are difficult to quantify precisely from surface electrocardiography.

exaly   +7 more sources

Early Repolarization Syndrome: Diagnostic and Therapeutic Approach

Frontiers in Cardiovascular Medicine, 2018
An early repolarization pattern can be observed in 1% up to 13% of the overall population. Whereas, this pattern was associated with a benign outcome for many years, several more recent studies demonstrated an association between early repolarization and
Ghassen Cheniti, , Takeshi Kitamura
exaly   +3 more sources

Repolarization reserve, arrhythmia and new drug development

Acta Pharmaceutica Sinica B, 2013
Repolarization-related lethal arrhythmias have led to the concept of “repolarization reserve”, which may help elucidate the relationship between K+ currents and other components of repolarization.
Yang Li, Yicheng Fu
exaly   +3 more sources

Abnormal Cardiac Repolarization in Thyroid Diseases: Results of an Observational Study

Frontiers in Cardiovascular Medicine, 2021
Background: The relationship between thyroid function and cardiac disease is complex. Both hypothyroidism and thyrotoxicosis can predispose to ventricular arrhythmia and other major adverse cardiovascular events (MACE), so that a U-shaped relationship ...
Assem Aweimer, Fabian Schiedat, Dominik Schöne, Gabi Landgrafe-Mende, Harilaos Bogossian, Andreas Mügge, Andreas Mügge, Polykarpos C. Patsalis, Michael Gotzmann, Ibrahim Akin, Ibrahim El-Battrawy, Johannes W. Dietrich, Johannes W. Dietrich, Johannes W. Dietrich, Johannes W. Dietrich   +14 more
doaj   +1 more source

Sarcoplasmic Reticulum Calcium Release Is Required for Arrhythmogenesis in the Mouse

Frontiers in Physiology, 2021
Dysfunctional sarcoplasmic reticulum Ca2+ handling is commonly observed in heart failure, and thought to contribute to arrhythmogenesis through several mechanisms. Some time ago we developed a cardiomyocyte-specific inducible SERCA2 knockout mouse, which
Andrew G. Edwards, Andrew G. Edwards, Halvor Mørk, Mathis K. Stokke, Mathis K. Stokke, Mathis K. Stokke, David B. Lipsett, Ivar Sjaastad, Ivar Sjaastad, Sylvain Richard, Ole M. Sejersted, William E. Louch, William E. Louch   +12 more
doaj   +1 more source

Electrocardiographic markers of myocardial conduction and repolarization in Boxer dogs [PDF]

Pesquisa Veterinária Brasileira, 2020
: Electrocardiographic markers have been used in people to classify arrhythmogenic risk. The aims of this study were to investigate electrocardiographic markers of conduction and repolarization in Boxers and non-Boxer dogs, and compare such findings ...
Elizabeth Regina Carvalho, Evandro Zacché, Michelli Fenerich, Aparecido Antônio Camacho, Julio P. Santos, Marlos G. Sousa   +5 more
doaj   +1 more source

Changes of repolarization parameters after left bundle branch area pacing and the association with echocardiographic response in heart failure patients

Frontiers in Physiology, 2022
Background: Left bundle branch area pacing (LBBAP) has become a safe and effective option for heart failure (HF) patients indicated for cardiac resynchronization therapy (CRT) and/or ventricular pacing, yet the response rate was only 70%.
Yao Li, Wenzhao Lu, Qingyun Hu, Chendi Cheng, Jinxuan Lin, Yu’an Zhou, Ruohan Chen, Yan Dai, Keping Chen, Shu Zhang   +9 more
doaj   +1 more source

Incorporating Latent Variables Using Nonnegative Matrix Factorization Improves Risk Stratification in Brugada Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background A combination of clinical and electrocardiographic risk factors is used for risk stratification in Brugada syndrome. In this study, we tested the hypothesis that the incorporation of latent variables between variables using nonnegative matrix ...
Gary Tse, Jiandong Zhou, Sharen Lee, Tong Liu, George Bazoukis, Panagiotis Mililis, Ian C. K. Wong, Cheng Chen, Yunlong Xia, Tsukasa Kamakura, Takeshi Aiba, Kengo Kusano, Qingpeng Zhang, Konstantinos P. Letsas   +13 more
doaj   +1 more source

Ionic current changes underlying action potential repolarization responses to physiological pacing and adrenergic stimulation in adult rat ventricular myocytes

Physiological Reports, 2023
This study aimed to simulate ventricular responses to elevations in myocyte pacing and adrenergic stimulation using a novel electrophysiological rat model and investigate ion channel responses underlying action potential (AP) modulations.
Luke A. Howlett, Harley Stevenson‐Cocks, Michael A. Colman, Matthew K. Lancaster, Alan P. Benson   +4 more
doaj   +1 more source

Increased Beat-to-Beat Variability of T-Wave Heterogeneity Measured From Standard 12-Lead Electrocardiogram Is Associated With Sudden Cardiac Death: A Case–Control Study

Frontiers in Physiology, 2020
IntroductionThe prognostic significance of beat-to-beat variability of spatial heterogeneity of repolarization measured from standard 12-lead ECG is not well-understood.MethodsWe measured the short-term variability of repolarization parameters, such as T-
Jenni J. Hekkanen, Tuomas V. Kenttä, Mira Anette E. Haukilahti, Janne T. Rahola, Lauri Holmström, Juha Vähätalo, Mikko P. Tulppo, Antti M. Kiviniemi, Lasse Pakanen, Lasse Pakanen, Olavi H. Ukkola, M. Juhani Junttila, Heikki V. Huikuri, Juha S. Perkiömäki   +13 more
doaj   +1 more source