Results 21 to 30 of about 43,223 (162)

Assessment of ventricular repolarization alterations in subjects with early repolarization

International Journal of Cardiology, 2004
Although the electrocardiographic (ECG) features of early repolarization (ER) have been studied extensively, no systematic quantification of ventricular repolarization in subjects with ER has been conducted so far.The objective of the present study was to evaluate ECG and spatial vectorcardiographic (VCG) descriptors of ventricular repolarization in ER
Dilaveris, P, Pantazis, A, Gialafos, E, Gialafos, J, Toutouzas, P, Stefanadis, C   +5 more
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Targeted Repolarization of Tumor‐Associated Macrophages via Imidazoquinoline‐Linked Nanobodies

Advanced Science, 2021
Tumor‐associated macrophages (TAMs) promote the immune suppressive microenvironment inside tumors and are, therefore, considered as a promising target for the next generation of cancer immunotherapies.
Evangelia Bolli, Maximilian Scherger, Sana M. Arnouk, Ana Rita Pombo Antunes, David Straßburger, Moritz Urschbach, Judith Stickdorn, Karen De Vlaminck, Kiavash Movahedi, Hans Joachim Räder, Sophie Hernot, Pol Besenius, Jo A. Van Ginderachter, Lutz Nuhn   +13 more
doaj   +1 more source

The Effect of Emotional Valence on Ventricular Repolarization Dynamics Is Mediated by Heart Rate Variability: A Study of QT Variability and Music-Induced Emotions

Frontiers in Physiology, 2019
BackgroundEmotions can affect cardiac activity, but their impact on ventricular repolarization variability, an important parameter providing information about cardiac risk and autonomic nervous system activity, is unknown. The beat-to-beat variability of
Michele Orini, Michele Orini, Faez Al-Amodi, Stefan Koelsch, Raquel Bailón, Raquel Bailón   +5 more
doaj   +1 more source

Arrhythmogenic Mechanisms in Hypokalaemia: Insights From Pre-clinical Models

Frontiers in Cardiovascular Medicine, 2021
Potassium is the predominant intracellular cation, with its extracellular concentrations maintained between 3. 5 and 5 mM. Among the different potassium disorders, hypokalaemia is a common clinical condition that increases the risk of life-threatening ...
Gary Tse, Gary Tse, Ka Hou Christien Li, Chloe Kwong Yee Cheung, Konstantinos P. Letsas, Aishwarya Bhardwaj, Abhishek C. Sawant, Tong Liu, Gan-Xin Yan, Henggui Zhang, Kamalan Jeevaratnam, Nazish Sayed, Nazish Sayed, Nazish Sayed, Shuk Han Cheng, Shuk Han Cheng, Shuk Han Cheng, Wing Tak Wong   +17 more
doaj   +1 more source

Modulation of Transmural Repolarization [PDF]

Annals of the New York Academy of Sciences, 2005
Abstract: Ventricular myocardium in larger mammals has been shown to be comprised of three distinct cell types: epicardial, M, and endocardial. Epicardial and M cell action potentials differ from endocardial cells with respect to the morphology of phase 1.
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Is myocardial repolarization duration associated with repolarization heterogeneity? [PDF]

Annals of Noninvasive Electrocardiology, 2017
BackgroundDispersion of repolarization is theorized as one mechanism by which myocardial repolarization prolongation causes lethal torsades de pointes, (TdP). Our primary purpose was to determine whether prolongation of myocardial repolarization as measured by the heart rate‐corrected J‐to‐T peak interval (JTpkc), is associated with repolarization ...
Keith A. Marill, Pat Dorsey, Anthony Holmes, Ketaki Muthal, Emily S. Miller, Joel Xue   +5 more
openaire   +2 more sources

Repolarization Reserve [PDF]

Circulation, 2008
A drug dose (and con-centration) that produces minimal QT prolongation in onepatient may, in an apparently indistinguishable subject, pro-duce marked QT prolongation and torsade de pointes. Thisvariability in response to an exogenous stressor is paralleledby variability in the extent to which a given mutation in thecongenital long-QT syndrome prolongs ...
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Role of the Purkinje-Muscle Junction on the Ventricular Repolarization Heterogeneity in the Healthy and Ischemic Ovine Ventricular Myocardium

Frontiers in Physiology, 2018
Alteration of action potential duration (APD) heterogeneity contributes to arrhythmogenesis. Purkinje-muscle junctions (PMJs) present differential electrophysiological properties including longer APD.
Marine E. Martinez, Marine E. Martinez, Marine E. Martinez, Richard D. Walton, Richard D. Walton, Richard D. Walton, Jason D. Bayer, Jason D. Bayer, Michel Haïssaguerre, Michel Haïssaguerre, Michel Haïssaguerre, Michel Haïssaguerre, Edward J. Vigmond, Edward J. Vigmond, Mélèze Hocini, Mélèze Hocini, Mélèze Hocini, Mélèze Hocini, Olivier Bernus, Olivier Bernus, Olivier Bernus   +20 more
doaj   +1 more source

Depolarization and repolarization dynamics after His‐bundle pacing: Comparison with right ventricular pacing and native ventricular conduction

Annals of Noninvasive Electrocardiology, 2022
Background The current study aimed to evaluate changes in electrical depolarization and repolarization parameters after His‐bundle pacing (HBP) compared with right ventricular pacing (RVP) and its association with ventricular arrhythmia (VA).
Satoshi Yanagisawa, Yasuya Inden, Ryo Watanabe, Naoki Tsurumi, Noriyuki Suzuki, Toshifumi Nakagomi, Masafumi Shimojo, Takashi Okajima, Shuro Riku, Koichi Furui, Kazumasa Suga, Rei Shibata, Toyoaki Murohara   +12 more
doaj   +1 more source

Polarization and Repolarization of Macrophages

Journal of Clinical and Cellular Immunology, 2015
Macrophages can acquire distinct phenotypes and biological functions depending on the microenvironment and the metabolic state. Macrophages classically activated by IFN-γ and/or microbial products display an M1 phenotype characterized by high expression of interleukin (IL)-12, inducible nitric oxide synthase (iNOS) and TNF-α.
FRATERNALE, ALESSANDRA, BRUNDU, SERENA, MAGNANI, MAURO   +2 more
openaire   +2 more sources