Results 41 to 50 of about 43,223 (162)

Early Repolarization in the Athlete

open access: yesJournal of the American College of Cardiology, 2009
An “abnormal” resting electrocardiogram is common in top-ranking, endurance-trained athletes ([1][1]). These abnormalities belong to physiological changes induced by training, as sinus bradycardia, high QRS and T-wave voltages, and early repolarization (ER), consisting of an elevation of QRS–
Bianco, Massimiliano, Zeppilli, Paolo
openaire   +2 more sources

Predisposition of functional genetic variants of A-kinase anchoring protein 10 toward acquired repolarization disorders in high-risk vascular surgery patients

open access: yesTherapeutics and Clinical Risk Management, 2018
Jowita Biernawska,1 Joanna Solek-Pastuszka,1 Arkadiusz Kazimierczak,2 Krzysztof Safranow,3 Mariusz Kaczmarczyk,4 Malgorzata Zegan-Baranska,5 Maciej Zukowski,5 Katarzyna Kotfis5 1Department of Anesthesiology and Intensive Therapy, Pomeranian Medical ...
Biernawska J   +7 more
doaj  

Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth

open access: yesMolecules
Tumor-associated macrophages (TAMs) are pivotal for tumor development and progression. Reprogramming the M2-like pro-tumoral behavior of TAMs towards the M1-like anti-tumor phenotype to unleash their potential against tumors has become one of the most ...
Xia Peng   +12 more
doaj   +1 more source

Electrophysiology Models for End-Stage Renal Disease Maladaptations That Promote Asystole

open access: yesReviews in Cardiovascular Medicine
Many patients with chronic renal impairment experience cardiac comorbidities throughout their lives, and the incidence of electrophysiological demise for patients with terminal renal impairment requiring renal replacement therapy is higher than in ...
Ikeotunye Royal Chinyere
doaj   +1 more source

Early Repolarization in Athletes [PDF]

open access: yesCirculation: Arrhythmia and Electrophysiology, 2016
Early repolarization (ER) on ECG was initially described in 1936 and has been considered a benign ECG finding for more than half a century.1,2 However, in 2008, a seminal study by Haissaguerre et al3 challenged this view by demonstrating an association between ER and an increased risk of idiopathic ventricular fibrillation (VF).
Philip, Aagaard   +3 more
openaire   +2 more sources

An extreme example of early repolarization

open access: yesThe Anatolian Journal of Cardiology, 2018
Once accepted as a benign phenomenon, electrocardiographic early repolarization pattern is now considered to have significant clinical importance. Haissaguerre et al. (1) were first to describe the possible association between early repolarization pattern and idiopathic ventricular fibrillation. Since then, numerous studies have documented the clinical
Altunbaş, Gökhan   +2 more
openaire   +2 more sources

Calcium- and Voltage-Dependent Dual Gating ANO1 is an Intrinsic Determinant of Repolarization in Rod Bipolar Cells of the Mouse Retina

open access: yesCells, 2020
TMEM16A/anoctamin1 (ANO1), a calcium (Ca2+)-activated chloride (Cl−) channel, has many functions in various excitable cells and modulates excitability in both Ca2+- and voltage-gating modes.
Sun-Sook Paik   +2 more
doaj   +1 more source

Electrocardiographic Strain Pattern Is Associated With Left Ventricular Concentric Remodeling, Scar, and Mortality Over 10 Years: The Multi‐Ethnic Study of Atherosclerosis

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundBoth ECG strain pattern and QRS measured left ventricular (LV) hypertrophy criteria are associated with LV hypertrophy and have been used for risk stratification.
Yuko Y. Inoue   +8 more
doaj   +1 more source

Macrophage‐derived Extracellular Vesicles Disguised AIEgen/IDO1 Inhibitor Nanoplatform Reactivate “Immune‐Hot” for Photothermal Immunotherapy via Multi‐Dimensionally Reprograms Tumor Microenvironment

open access: yesAggregate
Reversing the tumor microenvironment (TME) from “cold” to “hot” tumor represents a pivotal strategy to overcome the clinical bottleneck of poor response rates to immunotherapy in solid tumors.
Xue Li   +8 more
doaj   +1 more source

Reduction in Kv Current Enhances the Temporal Dispersion of the Action Potential in Diabetic Myocytes: Insights From a Novel Repolarization Algorithm

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundDiabetes is associated with prolongation of the QT interval of the electrocardiogram and enhanced dispersion of ventricular repolarization, factors that, together with atherosclerosis and myocardial ischemia, may promote the occurrence of ...
Marianna Meo   +12 more
doaj   +1 more source

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