Results 41 to 50 of about 57,164 (287)

Multifunctional Neutrophil Nanovesicles Induce Remodeling of Tumor Immune Microenvironment and Synergistic Multimodal Tumor Therapy

Advanced Functional Materials, EarlyView.
Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang, Cheng Ji, Xin‐Jian Fang, Yu Qian, Jiayuan Shi, Wenhui Liu, Baiyuan Fan, Yuan Zhong, Jiayi Wang, Dan Yu, Maoye Wang, Min Fu, Xiaoxin Zhang, Runbi Ji, Hélder A. Santos, Hongbo Zhang, Xu Zhang   +16 more
wiley   +1 more source

Repolarization dispersion in patients with systemic sclerosis

, 2020
OBJECTIVE: Systemic sclerosis (SSc) is associated with increased cardiac morbidity and mortality. Whether some electrocardiographic markers of arrhythmias predispose to early cardiogenic death in SSc remains controversial.
Gil Beeri, Yair Levi, Livneh, Avi, Avi Livneh, Udi Nussinovitch, Shiri Rubin, Nussinovitch, Udi, Beeri, Gil, Levi, Yair, Lidar, Merav, Merav Lidar, Rubin, Shiri   +11 more
core   +1 more source

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

Advanced Functional Materials, EarlyView.
The physical realization of artificial neurons is a critical challenge for energy‐efficient neuromorphic computing. This review presents a comprehensive analysis of the evolution of artificial neuron implementations from conventional CMOS to emerging post‐CMOS technologies.
Kannan Udaya Mohanan, Hocheon Yoo, Benoît H. Lessard, Ioannis Kymissis, Chang‐Hyun Kim   +4 more
wiley   +1 more source

Contribution of Depolarization and Repolarization Changes to J-Wave Generation and Ventricular Fibrillation in Ischemia

Frontiers in Physiology, 2020
Background: Activation delay in ischemic myocardium has been found to contribute to J-wave appearance and to predict ventricular fibrillation (VF) in experimental myocardial infarction.
Alena S. Tsvetkova, Jan E. Azarov, Jan E. Azarov, Jan E. Azarov, Olesya G. Bernikova, Alexey O. Ovechkin, Alexey O. Ovechkin, Marina A. Vaykshnorayte, Marina M. Demidova, Marina M. Demidova, Pyotr G. Platonov, Pyotr G. Platonov   +11 more
doaj   +1 more source

Detection of AP repolarization.

, 2023
(A) Repolarization time using moving average subtraction (MAS). MAS shows a secondary peak during the late phase of repolarization when the rapid repolarization slows down to reach the resting membrane potential.
Kareen L. K. Coulombe (8556033), Ulrike Mende (113749), Tae Yun Kim (738459), Bum-Rak Choi (738467), Allison Navarrete-Welton (14573300), Mark C. Daley (14573303), Peter Bronk (11722307), Arvin H. Soepriatna (6679826), Celinda M. Kofron (5159387)   +8 more
core   +1 more source

Bio‐Inspired Artificial Ionic Mechanoreceptor

Advanced Functional Materials, EarlyView.
A skin‐inspired artificial mechanoreceptor based on ionic interactions is presented for biomimetic tactile sensing. Pressure‐driven ionic redistribution within microfluidic channels generates a self‐powered electrical signal without external bias. The generated waveform exhibits mechanoreceptor‐like temporal features, including overshoot and undershoot,
Mohammad Akbari, Jeppe Don, Lasse A. N. Pedersen, John Noee, Rassoul Tabassian   +4 more
wiley   +1 more source

The early repolarization pattern [PDF]

, 2015
The term early repolarization has been in use for more than 50 years. This electrocardiographic pattern was considered benign until 2008, when it was linked to sudden cardiac arrest due to idiopathic ventricular fibrillation.
Yan, G.-X., Haïssaguerre, Michel, Potse, Mark, Potse, M., Tikkanen, J.T., Rosso, R., Sacher, Frederic, Wellens, Hein, Yan, Gan-Xin, Wellens, He., Huikuri, H.V., Sacher, F., Antzelevitch, Charles, Huikuri, Heikki V., Antzelevitch, C., Haissaguerre, M., Macfarlane, P.W., Tikkanen, Jani T., Macfarlane, Peter W., Rosso, Raphael   +19 more
core   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

T‐wave heterogeneity in standard resting 12‐lead ECGs is associated with 90‐day cardiac mortality in women following emergency department admission: A nested case–control study

Annals of Noninvasive Electrocardiology, 2021
Background We investigated whether T‐wave heterogeneity (TWH) can identify patients who are at risk for near‐term cardiac mortality. Methods A nested case–control analysis was performed in the 888 patients admitted to the Emergency Department (ED) of our
Felipe R. Monteiro, Ana B. Rabelo Evangelista, Bruce D. Nearing, Sofia A. Medeiros, Fernanda Tessarolo Silva, Giovanna C. Pedreira, Edward Ullman, Ernest V. Gervino, Richard L. Verrier   +8 more
doaj   +1 more source

Acetylcholine Reduces L-Type Calcium Current without Major Changes in Repolarization of Canine and Human Purkinje and Ventricular Tissue

Biomedicines, 2022
Vagal nerve stimulation (VNS) holds a strong basis as a potentially effective treatment modality for chronic heart failure, which explains why a multicenter VNS study in heart failure with reduced ejection fraction is ongoing.
Arie O. Verkerk, Illés J. Doszpod, Isabella Mengarelli, Tibor Magyar, Alexandra Polyák, Bence Pászti, Igor R. Efimov, Ronald Wilders, István Koncz   +8 more
doaj   +1 more source