Results 61 to 70 of about 57,164 (287)

Local areas of earlier repolarization cause epicardial repolarization heterogeneity in patients with apparently idiopathic ventricular fibrillation

, 2022
(The) Funding Acknowledgement: Type of funding sources: Foundation. Main funding source(s): Dutch Heart Foundation Background: Sudden cardiac arrest is often due to ventricular fibrillation (VF).
STOKS, Job, Nguyen, Y C, Ter Bekke, R M A, VAN REES, Bianca, Mihl, C, Volders, P G A, Cluitmans, M   +6 more
core   +1 more source

A Multifunctional Ionograsper Enabling Ion‐Redistribution Proximity Sensing and Structural‐Reconfiguration‐Driven Bidirectional Actuation

Advanced Materials, EarlyView.
A solid‐state ionic actuator integrates sensing, actuation, and memory within one material. A brief UV pulse induces long‐lasting deformation via coupled network rearrangement, dehydration, and rehydration, while ionic redistribution enables self‐powered sensing, supporting multifunctional, energy‐efficient soft robotic functions without continuous ...
Yong Min Kim, Jin Han Kwon, Hyeon Woo Yang, Sungryong Kim, Gyeong Rok Lee, Hong Chul Moon   +5 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Predisposition of functional genetic variants of A-kinase anchoring protein 10 toward acquired repolarization disorders in high-risk vascular surgery patients

Therapeutics and Clinical Risk Management, 2018
Jowita Biernawska,1 Joanna Solek-Pastuszka,1 Arkadiusz Kazimierczak,2 Krzysztof Safranow,3 Mariusz Kaczmarczyk,4 Malgorzata Zegan-Baranska,5 Maciej Zukowski,5 Katarzyna Kotfis5 1Department of Anesthesiology and Intensive Therapy, Pomeranian Medical ...
Biernawska J, Solek-Pastuszka J, Kazimierczak A, Safranow K, Kaczmarczyk M, Zegan-Baranska M, Zukowski M, Kotfis K   +7 more
doaj  

Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth

Molecules
Tumor-associated macrophages (TAMs) are pivotal for tumor development and progression. Reprogramming the M2-like pro-tumoral behavior of TAMs towards the M1-like anti-tumor phenotype to unleash their potential against tumors has become one of the most ...
Xia Peng, Siqi Yu, Lin Xu, Qinghua Wang, Lin Yang, Yi Su, Zhirou Xiong, Mengjie Shao, Meiyu Geng, Ao Zhang, Lei Zhang, Jing Ai, Chunyong Ding   +12 more
doaj   +1 more source

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Electrophysiology Models for End-Stage Renal Disease Maladaptations That Promote Asystole

Reviews in Cardiovascular Medicine
Many patients with chronic renal impairment experience cardiac comorbidities throughout their lives, and the incidence of electrophysiological demise for patients with terminal renal impairment requiring renal replacement therapy is higher than in ...
Ikeotunye Royal Chinyere
doaj   +1 more source

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

Advanced Science, EarlyView.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor, Gabrielle Juul, Jil Patel, Heran Pradhan, Gram Hepner, Jackson Jewell, Mark Bardin, Ryan Slusser, Abigail Glezer, Leda Klouda, Melikhan Tanyeri, Anita Saraf   +11 more
wiley   +1 more source

An extreme example of early repolarization

The Anatolian Journal of Cardiology, 2018
Once accepted as a benign phenomenon, electrocardiographic early repolarization pattern is now considered to have significant clinical importance. Haissaguerre et al. (1) were first to describe the possible association between early repolarization pattern and idiopathic ventricular fibrillation. Since then, numerous studies have documented the clinical
Altunbaş, Gökhan, Vuruşkan, Ertan, Sucu, Murat   +2 more
openaire   +2 more sources

Clinical Implication of Early Repolarization [PDF]

, 2013
Early repolarization described as J-point elevation with concaved ST segment, notch or slurred at terminal QRS complex on surface electrokardiography.
Yoga Yuniadi, Reza Octavianus, Budhi Setianto, Yuniadi, Yoga, Octavianus, Reza, Setianto, Budhi   +5 more
core   +1 more source