Results 31 to 40 of about 57,164 (287)
Modulation of Transmural Repolarization [PDF]
Abstract: Ventricular myocardium in larger mammals has been shown to be comprised of three distinct cell types: epicardial, M, and endocardial. Epicardial and M cell action potentials differ from endocardial cells with respect to the morphology of phase 1.
openaire +2 more sources
Is myocardial repolarization duration associated with repolarization heterogeneity? [PDF]
BackgroundDispersion of repolarization is theorized as one mechanism by which myocardial repolarization prolongation causes lethal torsades de pointes, (TdP). Our primary purpose was to determine whether prolongation of myocardial repolarization as measured by the heart rate‐corrected J‐to‐T peak interval (JTpkc), is associated with repolarization ...
Keith A. Marill +5 more
openaire +2 more sources
A drug dose (and con-centration) that produces minimal QT prolongation in onepatient may, in an apparently indistinguishable subject, pro-duce marked QT prolongation and torsade de pointes. Thisvariability in response to an exogenous stressor is paralleledby variability in the extent to which a given mutation in thecongenital long-QT syndrome prolongs ...
openaire +2 more sources
Alteration of action potential duration (APD) heterogeneity contributes to arrhythmogenesis. Purkinje-muscle junctions (PMJs) present differential electrophysiological properties including longer APD.
Marine E. Martinez +20 more
doaj +1 more source
Background The current study aimed to evaluate changes in electrical depolarization and repolarization parameters after His‐bundle pacing (HBP) compared with right ventricular pacing (RVP) and its association with ventricular arrhythmia (VA).
Satoshi Yanagisawa +12 more
doaj +1 more source
Early Repolarization in the Athlete
An “abnormal” resting electrocardiogram is common in top-ranking, endurance-trained athletes ([1][1]). These abnormalities belong to physiological changes induced by training, as sinus bradycardia, high QRS and T-wave voltages, and early repolarization (ER), consisting of an elevation of QRS–
Bianco, Massimiliano, Zeppilli, Paolo
openaire +2 more sources
Background The possible relationship between temporal variability of electrocardiographic spatial heterogeneity of repolarization and the risk of sudden cardiac death (SCD) in patients with coronary artery disease (CAD) is not completely understood ...
Janne T. Rahola +7 more
doaj +1 more source
Background: Hypertension (HTN) is linked to cardiac dysautonomia that can end up as life-threatening arrhythmias. The same can be screened by simple electrocardiogram (ECG)-based QTc (QT corrected for heart rate) interval which indicates repolarization ...
Jayesh Dalpatbhai Solanki +5 more
doaj +1 more source
Temporal Variability in Electrocardiographic Indices in Subjects With Brugada Patterns
IntroductionPatients with Brugada electrocardiographic (ECG) patterns have differing levels of arrhythmic risk. We hypothesized that temporal variations in certain ECG markers may provide additional value for risk stratification.
Sharen Lee +13 more
doaj +1 more source
Polarization and Repolarization of Macrophages
Macrophages can acquire distinct phenotypes and biological functions depending on the microenvironment and the metabolic state. Macrophages classically activated by IFN-γ and/or microbial products display an M1 phenotype characterized by high expression of interleukin (IL)-12, inducible nitric oxide synthase (iNOS) and TNF-α.
FRATERNALE, ALESSANDRA +2 more
openaire +2 more sources

