Results 11 to 20 of about 57,164 (287)

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve [PDF]

PLoS ONE, 2012
The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti-inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle.Ion currents were recorded using voltage clamp technique in canine single ventricular cells and action potentials were obtained from ...
Kristóf Attila, Husti Zoltán, Koncz István, Kohajda Zsófia, Szél Tamás, Juhász Viktor, Biliczki Péter, Jost Norbert László, Baczkó István, Papp Gyula, Varró András, Virág László   +11 more
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Assessment of ventricular repolarization alterations in subjects with early repolarization

International Journal of Cardiology, 2004
Although the electrocardiographic (ECG) features of early repolarization (ER) have been studied extensively, no systematic quantification of ventricular repolarization in subjects with ER has been conducted so far.The objective of the present study was to evaluate ECG and spatial vectorcardiographic (VCG) descriptors of ventricular repolarization in ER
Dilaveris, P, Pantazis, A, Gialafos, E, Gialafos, J, Toutouzas, P, Stefanadis, C   +5 more
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Early Repolarization Syndrome: Diagnostic and Therapeutic Approach [PDF]

Frontiers in Cardiovascular Medicine, 2018
An early repolarization pattern can be observed in 1% up to 13% of the overall population. Whereas, this pattern was associated with a benign outcome for many years, several more recent studies demonstrated an association between early repolarization and
Felix Bourier, Arnaud Denis, Arnaud Denis, Ghassen Cheniti, Ghassen Cheniti, Anna Lam, Konstantinos Vlachos, Masateru Takigawa, Masateru Takigawa, Takeshi Kitamura, Antonio Frontera, Josselin Duchateau, Josselin Duchateau, Josselin Duchateau, Thomas Pambrun, Thomas Pambrun, Nicolas Klotz, Nicolas Klotz, Nicolas Derval, Nicolas Derval, Frédéric Sacher, Frédéric Sacher, Frédéric Sacher, Pierre Jais, Pierre Jais, Pierre Jais, Michel Haissaguerre, Michel Haissaguerre, Michel Haissaguerre, Mélèze Hocini, Mélèze Hocini, Mélèze Hocini   +31 more
doaj   +2 more sources

Younger People Show More Changes in Repolarization with Exercise

, 2012
Purpose: Cardiac repolarization is a complex phenomenon that depends on heart rate (HR), autonomic nervous system (ANS) activity, age, gender and diseases/pathological conditions etc.
Andersson, Eva,, Lundahl, Gunilla, Bergfeldt, Lennart, Wecke, Liliane,, Nilsson, Johnny,   +4 more
core   +8 more sources

Repolarization reserve, arrhythmia and new drug development [PDF]

Acta Pharmaceutica Sinica B, 2013
Repolarization-related lethal arrhythmias have led to the concept of “repolarization reserve”, which may help elucidate the relationship between K+ currents and other components of repolarization.
Yang Li, Yicheng Fu
doaj   +2 more sources

Increased Beat-to-Beat Variability of T-Wave Heterogeneity Measured From Standard 12-Lead Electrocardiogram Is Associated With Sudden Cardiac Death: A Case–Control Study

Frontiers in Physiology, 2020
IntroductionThe prognostic significance of beat-to-beat variability of spatial heterogeneity of repolarization measured from standard 12-lead ECG is not well-understood.MethodsWe measured the short-term variability of repolarization parameters, such as T-
Jenni J. Hekkanen, Tuomas V. Kenttä, Mira Anette E. Haukilahti, Janne T. Rahola, Lauri Holmström, Juha Vähätalo, Mikko P. Tulppo, Antti M. Kiviniemi, Lasse Pakanen, Lasse Pakanen, Olavi H. Ukkola, M. Juhani Junttila, Heikki V. Huikuri, Juha S. Perkiömäki   +13 more
doaj   +1 more source

Sex, hormones, and repolarization [PDF]

Cardiovascular Research, 2002
There is increased awareness of the impact of gender and gonadal steroids on human cardiac rhythm and arrhythmias; e.g., drugs that prolong repolarization induce torsades de pointes (TdP) more frequently in women than men; female gender is an independent risk factor for syncope and sudden death in the congenital long QT syndrome; and the higher ...
Thai V, Pham, Michael R, Rosen
openaire   +2 more sources

Chronic Heart Failure Management: Monitoring Patients and Intercepting Exacerbations

Reviews in Cardiovascular Medicine, 2023
Despite significant progress in the field of therapy and management, chronic heart failure (CHF) still remains one of the most common causes of morbidity and mortality, especially among the elderly in Western countries.
Gianfranco Piccirillo, Federica Moscucci, Susanna Sciomer, Damiano Magrì   +3 more
doaj   +1 more source

Angiotensinogen and Angiotensin II Type 1 Receptor Gene Polymorphisms and Changes in Repolarization Parameters in Elderly Chinese: A 4-Year Follow-up Study

Kaohsiung Journal of Medical Sciences, 2008
Ventricular repolarization abnormality plays a crucial role in cardiac arrhythmia. Polymorphisms in renin—angiotensin system genes are associated with occurrence of ventricular arrhythmia. We previously demonstrated that subjects carrying the angiotensin
Ya-Ting Lee, Herng-Chia Chiu, Ho-Ming Su, Wen-Chol Voon, Tsung-Hsien Lin, Wen-Ter Lai, Sheng-Hsiung Sheu   +6 more
doaj   +1 more source

Diabetes mellitus attenuates the repolarization reserve in mammalian heart [PDF]

, 2007
Objective: In diabetes mellitus several cardiac electrophysiological parameters are known to be affected. In rodent experimental diabetes models changes in these parameters were reported, but no such data are available in other mammalian species ...
Lengyel, Csaba Attila, Papp, Julius Gyula, Biliczki, Péter, Tóth, Miklós, Jost, Norbert, Nánási, Péter Pál, Virág, László, Kocsis, Erzsébet, Varró, András, Bíró, Tamás, Skoumal, Réka, Kecskeméti, Valéria, Magyar, János   +12 more
core   +1 more source