Results 11 to 20 of about 43,223 (162)

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve [PDF]

PLoS ONE, 2012
The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti-inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle.Ion currents were recorded using voltage clamp technique in canine single ventricular cells and action potentials were obtained from ...
Kristóf Attila, Husti Zoltán, Koncz István, Kohajda Zsófia, Szél Tamás, Juhász Viktor, Biliczki Péter, Jost Norbert László, Baczkó István, Papp Gyula, Varró András, Virág László   +11 more
openaire   +5 more sources

Chronic Heart Failure Management: Monitoring Patients and Intercepting Exacerbations

Reviews in Cardiovascular Medicine, 2023
Despite significant progress in the field of therapy and management, chronic heart failure (CHF) still remains one of the most common causes of morbidity and mortality, especially among the elderly in Western countries.
Gianfranco Piccirillo, Federica Moscucci, Susanna Sciomer, Damiano Magrì   +3 more
doaj   +1 more source

Sex, hormones, and repolarization [PDF]

Cardiovascular Research, 2002
There is increased awareness of the impact of gender and gonadal steroids on human cardiac rhythm and arrhythmias; e.g., drugs that prolong repolarization induce torsades de pointes (TdP) more frequently in women than men; female gender is an independent risk factor for syncope and sudden death in the congenital long QT syndrome; and the higher ...
Thai V, Pham, Michael R, Rosen
openaire   +2 more sources

Angiotensinogen and Angiotensin II Type 1 Receptor Gene Polymorphisms and Changes in Repolarization Parameters in Elderly Chinese: A 4-Year Follow-up Study

Kaohsiung Journal of Medical Sciences, 2008
Ventricular repolarization abnormality plays a crucial role in cardiac arrhythmia. Polymorphisms in renin—angiotensin system genes are associated with occurrence of ventricular arrhythmia. We previously demonstrated that subjects carrying the angiotensin
Ya-Ting Lee, Herng-Chia Chiu, Ho-Ming Su, Wen-Chol Voon, Tsung-Hsien Lin, Wen-Ter Lai, Sheng-Hsiung Sheu   +6 more
doaj   +1 more source

Repolarization Dispersion Is Associated With Diastolic Electromechanical Discoordination in Children With Pulmonary Arterial Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Electromechanical dyssynchrony is a well described comorbidity in pulmonary arterial hypertension (PAH). ECG‐derived measurements reflective of diastolic dysfunction and electromechanical imaging markers are yet to be investigated.
Michal Schäfer, Benjamin S. Frank, D. Dunbar Ivy, Max B. Mitchell, Kathryn K. Collins, Pei‐Ni Jone, Johannes C. von Alvensleben   +6 more
doaj   +1 more source

Electrocardiographic manifestations of COVID-19: Effect on cardiac activation and repolarization

EClinicalMedicine, 2021
Background: Prolonged QT intervals are reported in patients with COVID-19. Additionally, virus particles in heart tissue and abnormal troponin levels have been reported.
Avni Thakore, James Nguyen, Simcha Pollack, Stefan Muehlbauer, Benjamin Chi, Derek Knight, Bhoomi Mehrotra, Joshua Stern, J. Jane Cao, Charles Lucore, Joseph Levine   +10 more
doaj   +1 more source

Refining repolarization reserve [PDF]

Heart Rhythm, 2011
A body of cellular and molecular studies over the past 15 years has demonstrated that the fundamental molecular lesion in the drug-induced long QT syndrome (LQTS) is block of the repolarizing potassium current IKr, the “rapid” component of the repolarizing potassium current that was initially termed IK.1,2 Further, decreased IKr due to KCNH2 mutations ...
Dan M, Roden, Robert L, Abraham
openaire   +2 more sources

Analysis of 24-h Rhythm in Ventricular Repolarization Identifies QT Diurnality As a Novel Clinical Parameter Associated with Previous Ventricular Arrhythmias in Heart Failure Patients

Frontiers in Physiology, 2017
Introduction: Cardiac repolarization abnormalities are among the major causes of ventricular arrhythmias and sudden cardiac death. In humans, cardiac repolarization duration has a 24-h rhythm.
Bastiaan C. Du Pre, Bastiaan C. Du Pre, Linda W. Van Laake, Matthias Meine, Jeroen F. Van der Heijden, Pieter A. Doevendans, Marc A. Vos, Toon A. B. Van Veen   +7 more
doaj   +1 more source

Repolarization properties of copper-containing crystals of triglycine sulfate

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2022
The paper presents the results of the analysis of experimental dielectric hysteresis loops and field dependens of polarization switching of initial and annealed crystals of triglycine sulfate, doped copper (the concentration range (4,2–8,7) 10-3 wt ...
N.N. Bolshakova, N.Yu. Druginina, A.I. Ivanova, D.N. Pavlova, B.B. Ped`ko, E.M. Semenova   +5 more
doaj   +1 more source

Electrocardiogram abnormalities and prognosis in COVID-19

Frontiers in Cardiovascular Medicine, 2022
BackgroundCOVID-19 is a major pandemic with potential cardiovascular complications. Few studies have focused on electrocardiogram (ECG) modifications in COVID-19 patients.Method and resultsWe reviewed from our database all patients referred to our ...
Gabriel Chevrot, Marie Hauguel-Moreau, Marie Hauguel-Moreau, Marion Pépin, Marion Pépin, Antoine Vieillard-Baron, Antoine Vieillard-Baron, Antoine Vieillard-Baron, Anne-Sophie Lot, Mounir Ouadahi, Hélène Hergault, Vincent Aïdan, Ségolène Greffe, Adrien Costantini, Olivier Dubourg, Olivier Dubourg, Sébastien Beaune, Sébastien Beaune, Nicolas Mansencal, Nicolas Mansencal   +19 more
doaj   +1 more source