Results 111 to 120 of about 14,230,890 (402)
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
Recent Developments in Cardiac Contractility Modulation for Heart Failure [PDF]
Texas Heart Institute JournalNone.
Joshua R. Hirsch, MD, Hamid Afshar, MD
doaj +1 more source
Generative Action Description Prompts for Skeleton-based Action Recognition [PDF]
arXiv, 2022 Skeleton-based action recognition has recently received considerable attention. Current approaches to skeleton-based action recognition are typically formulated as one-hot classification tasks and do not fully exploit the semantic relations between actions.
arxiv
Membrane Potential Changes in Dendritic Spines during Action Potentials and Synaptic Input
Journal of Neuroscience, 2009 Excitatory input onto many neurons in the brain occurs onto specialized projections called dendritic spines. Despite their potential importance in neuronal function, direct experimental evidence on electrical signaling in dendritic spines is lacking as ...
L. Palmer, G. Stuart
semanticscholar +1 more source
The Nature of the Action Potential
ArXivWe demonstrate that our recently developed theory of electric field wave propagation in anisotropic and inhomogeneous brain tissues, which has been shown to explain a broad range of observed coherent synchronous brain electrical processes, also explains the spiking behavior of single neurons, thus bridging the gap between the fundamental element of ...
Galinsky, Vitaly L., Frank, Lawrence R.
openaire +3 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Analogue modulation of back-propagating action potentials enables dendritic hybrid signalling
Nature Communications, 2016 ‘Analogue’ modulation by somatic membrane potentials can modify ‘digital’ axonal action potentials. Here, the authors show that analogue modulation can occur in back-propagating dendritic action potentials and calcium signals, leading to signal ...
János Brunner, János Szabadics
doaj +1 more source
Distribution of Action Potential Duration and T-wave Morphology: a Simulation Study [PDF]
arXiv, 2009 The results of a simulation study of the action potential duration (APD) distribution and T-wave morphology taking into account the midmyocardial cells (M-cells) concept are described. To investigate the effect of M-cells we present a computer model in which ion channel action potential formulations are incorporated into three-dimensional whole heart ...
arxiv
Journal of Neuroscience, 2009 Long-term potentiation (LTP) requires postsynaptic depolarization that can result from EPSPs paired with action potentials or larger EPSPs that trigger dendritic spikes.
J. Hardie, N. Spruston
semanticscholar +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source