Results 141 to 150 of about 14,230,890 (402)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Detecting the unique representation of motor-unit action potentials in the surface electromyogram.
Journal of Neurophysiology, 2008 This study investigated the relative proportion of motor-unit action potentials that are uniquely represented in the simulated and experimental surface electromyogram (EMG).
D. Farina +3 more
semanticscholar +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
From substance fermentation to action potential in modern science (part two)
Revista de la Facultad de Medicina, 2018 Introduction: After conducting a bibliographical review on the works of various researchers at different times to explain the phenomenon of the transmission of nerve impulses, it is observed that since the eighteenth century, when modern science was born,
John Barco-Rios +2 more
doaj +1 more source
Experimental Biology and Medicine, 1933 The following observations, some confirmatory, based on experiments on 8 cats and 2 monkeys, were made during an exploration of the cerebral cortex and underlying structures for spontaneous and evoked activity. Anatomical relations given are only approximate; the work is being continued with the aid of a Horsley-Clark stereotaxic instrument.
W. H. Marshall, L. J. Saul, R. W. Gerard
openaire +2 more sources
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Topological Pressure for sub-additive potentials of amenable group actions [PDF]
arXiv, 2011 We define the topological pressure for any sub-additive potentials of the countable discrete amenable group action and any given open cover. A local variational principle for the topological pressure is established.
arxiv
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
Slow synaptic transmission in frog sympathetic ganglia [PDF]
, 1986 Bullfrog ganglia contain two classes of neurone, B and C cells, which receive different inputs and exhibit different slow synaptic potentials. B cells, to which most effort has been directed, possess slow and late slow EPSPs.
Adams, P. R. +5 more
core +2 more sources