Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Coordinated regulation of timing and strength of synaptic outputs by adrenergic receptors through control of action potentials in Purkinje cells. [PDF]
Furukawa K, Kawaguchi SY.
europepmc +1 more source
Increased Event-Related Potentials and Alpha-, Beta-, and Gamma-Activity Associated with Intentional Actions [PDF]
Susanne Karch +8 more
openalex +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
High-speed voltage imaging of action potentials in molecular layer interneurons reveals sensory-driven synchrony that augments movement. [PDF]
Brown ST +6 more
europepmc +1 more source
Bright and sensitive red voltage indicators for imaging action potentials in brain slices and pancreatic islets. [PDF]
Han Y +12 more
europepmc +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Contributions of action potentials to scalp EEG: Theory and biophysical simulations. [PDF]
Brake N, Khadra A.
europepmc +1 more source

