Results 81 to 90 of about 14,230,890 (402)
Alzheimer’s disease (AD) is a degenerative disorder characterized by progressive cognitive decline and memory loss. The few contemporary therapies may ease symptoms and/or slow down AD progression but cannot cure the disease.
Corina S. Drapaca
doaj +1 more source
Fetal and infant brains are rich in maternally derived taurine. We previously demonstrated that taurine action regulates the cation-chloride cotransporter activity and the differentiation and radial migration of pyramidal neuron progenitors in the ...
Yasushi Hosoi+7 more
doaj +1 more source
This investigation explores using the beta function formalism to calculate analytic solutions for the observable parameters in rolling scalar field cosmologies.
Thompson, Rodger I.
core +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Modeling specific action potentials in the human atria based on a minimal reaction-diffusion model
We present an effective method to model empirical action potentials of specific patients in the human atria based on the minimal model of Bueno-Orovio, Cherry and Fenton adapted to atrial electrophysiology.
Lind, Pedro G.+2 more
core +2 more sources
Spectral action, Weyl anomaly and the Higgs-Dilaton potential [PDF]
We show how the bosonic spectral action emerges from the fermionic action by the renormalization group flow in the presence of a dilaton and the Weyl anomaly. The induced action comes out to be basically the Chamseddine-Connes spectral action introduced in the context of noncommutative geometry.
arxiv +1 more source
Sub-action Prototype Learning for Point-level Weakly-supervised Temporal Action Localization [PDF]
Point-level weakly-supervised temporal action localization (PWTAL) aims to localize actions with only a single timestamp annotation for each action instance. Existing methods tend to mine dense pseudo labels to alleviate the label sparsity, but overlook the potential sub-action temporal structures, resulting in inferior performance.
arxiv
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
The DBI Action, Higher-derivative Supergravity, and Flattening Inflaton Potentials [PDF]
In string theory compactifications it is common to find an effective Lagrangian for the scalar fields with a non-canonical kinetic term. We study the effective action of the scalar position moduli of Type II D$p$-branes.
Bielleman, Sjoerd+4 more
core +4 more sources
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source