Results 141 to 150 of about 30,174 (282)
British Journal of Haematology, EarlyView.Summary Dynamic interactions between mutated haematopoietic cells and immune cells are key drivers of myelodysplastic neoplasms (MDS) initiation and progression. Regulatory T cells (Tregs) are central mediators of immunosuppression in MDS. We thus aimed to characterize Treg subpopulations in the bone marrow (BM) of MDS patients and to explore their ...
Romain Vazquez +18 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source
Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal
Periodontology 2000, EarlyView., 2023 Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra +3 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Obesity involves profound disruptions in neuronal circuits, neuroendocrine communication and the endocannabinoid system. While global blockade of cannabinoid CB1 receptors improves metabolism, its clinical use is limited by neuropsychiatric side effects.
Oriane Onimus +7 more
wiley +1 more source
Crise et action publique : entre ambivalence et connaissance
, 2015 L'ouvrage "interroge le continuum des relations entre "crise" et action publique. L'introduction revient sur les discours sur la crise de l'école ou de l'éducation et met en évidence la nécessité de les déconstruire.
Becquet, Valérie, Vulbeau, Alain
core +2 more sources
, 2019 Dans cet article, qui s?appuie sur des faits observés dans le cas argentin, on analyse un phénomène largement étudié par la criminologie, la sécurité privée et la pluralisation de l?action de police, cette fois-ci du point de vue de la sociologie de l ...
Lorenc Valcarce, Federico Mario
core
Canadian Public Administration, EarlyView.Abstract This article argues that policy learning is essential for effective innovation policy. The ability to learn from past experiments in a reflexive fashion is a prerequisite for effective policy design. The article responds to the call for more applied research to compliment the theoretical framing of policy learning in the literature.
David A. Wolfe, Travis Southin
wiley +1 more source
Canadian Public Administration, EarlyView.Abstract This research examined the relationship between digital competency and perceived organizational support among Nova Scotia public servants and MPA students. Findings revealed a non‐linear developmental progression where reliance on external validation systematically diminished as expertise matures.
Warwick Young, Kristian Suen
wiley +1 more source
Action publique, Agriculture & Biodiversité : cas de l'AOC Saumur-Champigny
, 2010 Action publique, Agriculture & Biodiversité : cas de l'AOC Saumur ...
Montembault, David +2 more
core +1 more source