Results 221 to 230 of about 2,560,141 (301)

The effect of identity-related interventions on physical activity- and smoking-related identities and behavior: a mixed-methods systematic review. [PDF]

Syst Rev
van Vliet MHM, Penfornis KM, Gebhardt WA, von Haeseler EF, Chavannes NH, Versluis A, Meijer E.   +6 more
europepmc   +1 more source

Central Film School London : Review for Educational Oversight by the Quality Assurance Agency for Higher Education, December 2012 [PDF]

, 2013

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Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Integrated quality and enhancement review : summative review : Stoke on Trent College [PDF]

, 2011

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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

UncerTrans: uncertainty-aware temporal transformer for early action prediction. [PDF]

Sci Rep
Zhai X, Liu Y.
europepmc   +1 more source

Midlands International College Review for Educational Oversight by the Quality Assurance Agency for Higher Education [PDF]

, 2012

core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Life-Course Framework for Institute-Based Surveillance of Overweight, Obesity, and Metabolic Risk Factors in India: Protocol for Surveillance System Development. [PDF]

JMIR Res Protoc
Challa SR, Dash B.
europepmc   +1 more source

Central College London : Review for Educational Oversight by the Quality Assurance Agency for Higher Education, September 2012 [PDF]

, 2012

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