Results 141 to 150 of about 8,600,421 (324)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Digitally Quantifying Growth and Verdancy of Lolium Plants In Vitro

open access: yesPlants
The image analysis of plants provides an opportunity to measure changes in growth and physiology quantitatively, and non-destructively, over time providing significant advantages over traditional methods of assessment which often rely on qualitative and ...
Mara B. Depetris   +2 more
doaj   +1 more source

Where is the Action? [PDF]

open access: yes
Taking a set of studies about business action as the empirical starting-point, this paper looks at the various ways in which action is represented.
Andersson, Per, Kjellberg, Hans
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Preventing the Silent Threat: A Perspective on Preparing Bangladesh for Human Metapneumovirus (HMPV)

open access: yesHealth Science Reports
Background and Aims Human metapneumovirus (HMPV) is a significant respiratory pathogen with a global presence that disproportionately affects young children and the elderly.
Md. Jubayer Hossain   +3 more
doaj   +1 more source

Agricultural Risk Management - Experiences from an Action Research Approach [PDF]

open access: yes
A new model for risk management in agriculture is described in the paper. The risk model is constructed as a context dependent process, which includes four main phases.
Andersen, Henning   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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