Results 161 to 170 of about 26,919,379 (332)

Applying Experiential Action Learning Pedagogy to an Intensive Course to Enhance Capacity to Conduct Community-Based Participatory Research

, 2019
Chris M. Coombe, Amy J. Schulz, Wilma Brakefield-Caldwell, Carol Gray Brunton, Jaime Guzmán, Edith C. Kieffer, Toby C. Lewis, Ángela Reyes, Zachary Rowe, Barbara A. Israel   +9 more
openalex   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Preventing the Silent Threat: A Perspective on Preparing Bangladesh for Human Metapneumovirus (HMPV)

Health Science Reports
Background and Aims Human metapneumovirus (HMPV) is a significant respiratory pathogen with a global presence that disproportionately affects young children and the elderly.
Md. Jubayer Hossain, Soniya Akter Sony, Fatema Tuj Johora Fariha, Sajjad Hossen   +3 more
doaj   +1 more source

Raising the Profile of Participatory Action Research at the 2010 Global Symposium on Health Systems Research

, 2011

openalex   +1 more source

Action research

Communications of the ACM, 1999
Avison, D., Lau, F., Myers, M., Nielsen, Peter Axel   +3 more
openaire   +2 more sources

Multi-site Action Research

, 2007
Classical action research within single organizations has become a well established and differentiated approach since its inception more than six decades ago.
Fuller-Rowell, Thomas
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Research on collaboration in action.

International Journal of Action Research, 2006
"In this paper I will focus on the psychological dynamics of multiparty collaboration, illustrated by two projects in which I have been engaged. First I describe what I mean by multiparty collaboration. Next, I outline the principles of designing and executing action research projects. The theoretical background for these principles is derived from the
openaire   +2 more sources