Results 41 to 50 of about 406,735 (259)
A Theory of Flagship Species Action
Conservation & Society, 2015 The flagship species approach is an enduring strategy in conservation. Academic discussion on flagship species has focussed on two dimensions: on what basis should they be selected and how have they been put to use.
Paul Jepson, Maan Barua
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Learning to Become Youth. An Action Theory Approach
Outlines, 2006 Youth is a historical construction and an answer to a specific challenge of individualisation in biography. And, as a historical and social construction, youth has to be learned. This article focuses on youth development from an action or activity theory
Sven Mørch
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Social Sciences and Humanities OpenPolitical trust is a well-used construct and serves both as an explanation and an outcome in the social sciences. Considering the importance of the construct, relatively little attention has been allocated to its measurement.
Oskar Rydén +5 more
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Action-Guidance, Oppression, and Nonideal Theory
Feminist Philosophy Quarterly, 2016 Lisa Tessman’s Moral Failure: On the Impossible Demands of Morality raises important questions about ideal theory, oppression, and the role of action guidance in normative philosophy.
Lisa H Schwartzman
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
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Theory and practice of socio-educational action
Teoría de la Educación: Revista Interuniversitaria, 2013 The aim of this paper is to present a training proposal to allow the realization of the training of professionals in both social and educational ways.
Carmen PEREIRA DOMÍNGUEZ +2 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
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