Results 141 to 150 of about 78,660 (285)

Prediction of treatment response in infantile epileptic spasms syndrome using EEG phase–amplitude coupling

Epilepsia Open, EarlyView.
Abstract Objective Treatment selection for infantile epileptic spasms syndrome (IESS) is complex and multifaceted, and currently no electroencephalogram (EEG) biomarkers can guide this decision by predicting treatment response. We tested the predictive value of phase–amplitude coupling (PAC) as IESS patients are known to have elevated PAC.
Soudeh Mostaghimi, Marco A. Pinto‐Orellana, Nathaniel Green, Daniel W. Shrey, Makoto Miyakoshi, Shaun A. Hussain, Beth A. Lopour   +6 more
wiley   +1 more source

Sialidosis type I: How to alleviate disabling myoclonic seizures?—A multicenter analysis of eight cases and review of the literature

Epilepsia Open, EarlyView.
Abstract Objective Sialidosis type I (ST‐1) is an autosomal‐recessive, very rare, progressive lysosomal storage disorder caused by pathogenic variants in NEU1. It is clinically characterized by progressive ataxia, myoclonic seizures (MS), bilateral tonic–clonic seizures (BTCS), and distinctive ophthalmological findings.
Janina Gburek‐Augustat, I‐Chun Lee, Marica Rubino, Vehap Topçu, Melissa Chavez‐Castillo, Shao Ching Tu, Marwan Shinawi, Isabel Alfradique‐Dunham, Manouela Valtcheva, Astrid Adarmes‐Gómez, Daniel Macias‐Garcia, Laura Laura Muñoz‐Delgado, Silvia Jesús, Pablo Mir, Andreas Merkenschlager, Antonietta Coppola   +15 more
wiley   +1 more source

Tracking Glucose Trends, Unveiling Clinical Patterns: Insights From Continuous Glucose Monitoring in Patients at the Extreme of BMI and Eating Disorders Psychopathology

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Disturbances of glucose homoeostasis are claimed to act as both a consequence and maintaining factor in eating disorders (EDs). This study explored glucose trends and their association with real‐time food intake and self‐report eating psychopathology in a sample of patients with anorexia nervosa (AN) and binge‐eating disorder (BED ...
Marianna Rania, Concetta Irace, Raffaella Sacco, Mariateresa Bevacqua, Elvira Anna Carbone, Antonio Cutruzzolà, Maria Chiara Pelle, Franco Arturi, Cristina Segura‐Garcia   +8 more
wiley   +1 more source

Short-term efficacy of peripheral nerve stimulation for essential tremor in a randomized double-blind controlled trial

Scientific Reports
Peripheral nerve stimulation (PNS) demonstrates promise for some neurological conditions. However, its effectiveness for essential tremor (ET) requires further research.
Reza Samiee, Melika Jameie, Masoud Rahmati, Mehdi Azizmohammad Looha, Sheida Mobader, Abbas Tafakhori, Payam Sarraf, Hamed Amirifard, Sakineh Ranji Burachaloo, Mojdeh Ghabaee, Mobina Amanollahi, Zohreh Tajabadi, Mohammad Hossein Harirchian   +12 more
doaj   +1 more source

Dysfunction of parvalbumin neurons in the cerebellar nuclei produces an action tremor. [PDF]

J Clin Invest, 2020
Zhou M, Melin MD, Xu W, Südhof TC.
europepmc   +1 more source

Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra‐Targeted Tumor α‐Therapy

Exploration, EarlyView.
Encapsulating 223Ra in Au10‐12 nanoclusters and functionalizing them with RGD peptides enables targeted α‐therapy and immune microenvironment remodeling in non‐osseous tumors like triple‐negative breast cancer. This study establishes a foundational framework for novel 223Ra‐labeled α‐radiopharmaceuticals and shows strong potential for clinical ...
Yifei Jiang, Huizhen Yang, Guoping Jia, Wangxi Hai, Rongyi Huang, Peng Wang, Min Zhang, Danni Li, Yizhou Chen, Xiao Li, Biao Li, Chunfu Zhang   +11 more
wiley   +1 more source

Programmable crack dynamics engineering enables flexible strain sensors with high linearity

FlexMat, EarlyView.
First‐decoupling theoretical framework of crack evolution elucidating the control methods, mechanistic insights, and structure‐activity relationships is established. Crack propagation from uncontrollable randomness systematically evolves into spatially ordered states.
Chunjin Wu, Shaolong Wang, Xu Wang, Heng Zhu, Yongliang Tian, Xinchen Jiang, Xin Rao, Yutong Han, Changrun Wang, Wen‐Yong Lai   +9 more
wiley   +1 more source

ANTI-TREMOR ACTION OF PROPRANOLOL (INDERAL)

Japanese Journal of Pharmacology, 1967
G, Achari, S P, Sinha
openaire   +2 more sources

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

iNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu, Jinmei Sun, Lili Hu, Xin Chen, Jinying Han, Liuzhenxiong Yu, Siyu Fan, Rong Ye, Kai Wang, Gong‐Jun Ji, Panpan Hu   +10 more
wiley   +1 more source