Results 41 to 50 of about 315,040 (261)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Adsorption capacity of coal-based activated carbon in advanced treatment of drinking water

矿业科学学报, 2021
Activated carbon is the core material in the process of advanced treatment of drinking water. Evaluating the adsorption capacity of activated carbon accurately is the basis of its selection in practical applications.
Wan Chaoran, Xie Qiang, Liu Deqian, Zhou Yihuan, Wu Haotian, Yang Shuai   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Synthesis and characterization of magnetic activated carbon manufactured from palm stones by physical activation to remove lead from aqueous solution

Desalination and Water Treatment
Activated carbon (AC) generated from palm date stone through physical activation and magnetic activated carbon (MAC) fabricated through co-precipitation of Fe3O4 were examined for their efficacy in removing lead (II) from aqueous solutions in batch mode.
Ali Ahmed Ali, Hayder M. Abdul-Hameed
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sintesis Karbon Aktif Berbahan Dasar Mikroalga Chlorella vulgaris Menggunakan Aktivator KOH dan Iradiasi Gelombang Mikro

Rekayasa Mesin, 2019
Microalgae Chlorella vulgaris has been used as a raw material in the synthesis of powdered activated carbon. Dry microalgae was pyrolyzed at a temperature of 500oC for 30 minutes to obtain microalgae charcoal.
Agung Sukoyo, Gunomo Djoyowasito, Yusuf Wibisono   +2 more
doaj   +1 more source

Removal of benzene, MTBE and toluene from contaminated waters using biochar-based liquid activated carbon

Scientific Reports, 2022
Fuel components such as benzene, toluene, and methyl tertiary-butyl ether (MTBE) are frequently detected pollutants in groundwater resources. Ex-situ remediation technologies by activated carbon have been used for treatment for many years.
F. Alshahrani, B. Tawabini, T. Saleh, M. Alrayaan, S. Alaama, R. Nasser, P. Soupios, P. Kirmizakis, M. Mahmoud, T. Oyehan, E. Safi   +10 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Synthesis, characterisation of agricultural biomass derived activated carbon and its applications

Materials Research Express
As the world moves toward greener energy generation methods and cleaner environments, activated carbon produced from ligninocellulosic resources has attracted unexpected interest due to its easy availability, and economic, renewable, and biodegradable ...
Shweta Priya, Salmataj S A, B Anusha, Pushpanjali Bhat   +3 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source