Results 51 to 60 of about 388,983 (311)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Scale-up activation of carbon fibres for hydrogen storage

, 2010
In a previous study, we investigated, at a laboratory scale, the chemical activation of two different carbon fibres (CF), their porosity characterization, and their optimization for hydrogen storage [1]. In the present work, this study is extended to: (i)
Marco Lozar, Juan Pablo, Cazorla-Amorós, Diego, Kunowsky, Mirko, Linares-Solano, Angel   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparative study on filtration effect of powdered activated carbon and activated carbon fiberboard on strong-flavor Baijiu [PDF]

Zhongguo niangzao
In this study, the filtration performance of activated carbon fiberboard (AKS1, AKS2, AKS4, R11, R33, R54) and powdered activated carbon on the filtration effect of 48%vol strong-flavor (Nongxiangxing) Baijiu was systematically compared.
XUE Runping, XIE Zhengmin, ZHENG Jia, ZHAO Dong, LI Maochun, HUANG Jian, YE Huaxia, ZHANG Qian, WANG Xingming
doaj   +1 more source

Simulation Study for the Adsorption of Carbon Disulfide on Hydroxyl Modified Activated Carbon

Molecules, 2023
In this study, grand canonical Monte Carlo simulations (GCMC) and molecular dynamics simulations (MD) were used to construct models of activated carbon with hydroxyl-modified hexachlorobenzene basic unit contents of 0%, 12.5%, 25%, 35% and 50%.
Xiangyu Cui, Penghui Li, Baohua Hu, Teng Yang, Haichao Fu, Shuai Chen, Xiaolai Zhang   +6 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Carbon Dioxide Adsorption by a High-Surface-Area Activated Charcoal

, 2023
An activated carbon (AC) with a high surface area of 4320.7 m2/g was synthesized via the chemical and thermal processing of walnut residues. The resulting activated charcoal was characterized by various techniques, including Brunauer–Emmett&ndash ...
Gerhard F. Swiegers, Assim A. Sabah, Ahmed S. Ahmed, Mohammed Alsultan   +3 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Synthesis and characterization of magnetic activated carbon manufactured from palm stones by physical activation to remove lead from aqueous solution

Desalination and Water Treatment
Activated carbon (AC) generated from palm date stone through physical activation and magnetic activated carbon (MAC) fabricated through co-precipitation of Fe3O4 were examined for their efficacy in removing lead (II) from aqueous solutions in batch mode.
Ali Ahmed Ali, Hayder M. Abdul-Hameed
doaj   +1 more source

Carbon Capture: Theoretical Guidelines for Activated Carbon-based CO2 Adsorption Material Evaluation

, 2023
Activated carbon (AC)-based materials have shown promising performance in carbon capture, offering low cost and sustainable sourcing from abundant natural resources.
Asmita, Jana, Seth, Snyder, Yingchao, Yang, Jin, Qian, Qiang, Xu, Manish , Neupane, Drew M., Glenna, Yuqing , Meng, Haiyan, Zhao, Yixiao , Wang, Lucun, Wang   +10 more
core   +1 more source