Results 71 to 80 of about 388,983 (311)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Influencing Factors of the Carbon Adsorption Properties of Radon

Journal of Isotopes, 2018
In order to prevent the indoor radon from being harmful to human health, it is necessary to accurately measure the indoor air radon concentration. Among them, the activated carbon box is one of the commonly used methods, but its accurate measurement is ...
ZHANG Yanli1,2;TANG Xuan1,2;CAO Zhongsheng1,2;TIAN Shihong3;LI Wenzhong1,2
doaj   +1 more source

Biomass-Derived N-Doped Activated Carbon from Eucalyptus Leaves as an Efficient Supercapacitor Electrode Material

, 2023
Biomass-derived activated carbon is one of the promising electrode materials in supercapacitor applications. In this work bio-waste (oil extracted from eucalyptus leaves) was used as a carbon precursor to synthesize carbon material with ZnCl2 as a ...
Puttapati Sampath Kumar, Dinesh Bejjanki, Vijay Bhooshan Kumar, Praveen Banothu   +3 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

STUDY PORE CHARACTERIZATION OF γ-ALUMINA – ACTIVATED CARBON COMPOSITE MADE OF CASSAVA PEELS (Manihot esculenta Cranz)

Alchemy, 2015
A composite of γ-alumina and activated carbon made of cassava peels was studied in terms of its pore structures and its properties. The objective of this study was to determine the interaction and structure, as well as the character and pore size of γ ...
Hartini Hartini, Yuniawan Hidayat, Mudjijono Mudjijono   +2 more
doaj   +1 more source

Superhydrophobic Activated Carbon-Coated Sponges for Separation and Absorption

, 2013
Highly porous activated carbon with a large surface area and pore volume was synthesized by KOH activation using commercially available activated carbon as a precursor.
Deng, Weiqiao, Sun, Hanxue, Li, An, Liang, Weidong, 邓伟侨, Zhu, Zhaoqi, La, Peiqing, An Li, Zhao, Xinhong   +8 more
core   +1 more source

Nanoporous Versus Nanoparticulate Carbon-Based Materials for Capacitive Charge Storage

, 2020
This article reviews recent progresses in the preparation and supercapacitor applications of selected nanoporous and nanoparticulate carbon-based materials, namely activated carbons, graphenes and carbon nanotubes and their composites with redox ...
Chen, George Zheng, George Zheng Chen, Xiaoyue Hao, Yao Chen, Hao, Xiaoyue, Chen, Yao   +5 more
core   +1 more source