Results 31 to 40 of about 153,708 (298)

Commissioning of the vacuum system of the KATRIN Main Spectrometer [PDF]

open access: yes, 2016
The KATRIN experiment will probe the neutrino mass by measuring the beta-electron energy spectrum near the endpoint of tritium beta-decay. An integral energy analysis will be performed by an electro-static spectrometer (Main Spectrometer), an ultra-high ...
Arenz, M.   +150 more
core   +3 more sources

The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington’s disease [PDF]

open access: yes, 2020
Objective Compromised brain cholesterol turnover and altered regulation of brain cholesterol metabolism have been allied with some neurodegenerative diseases, including Huntington’s disease (HD).
Alves, Sandro   +12 more
core   +1 more source

Glutathione Metabolism in Renal Cell Carcinoma Progression and Implications for Therapies [PDF]

open access: yes, 2019
A significantly increased level of the reactive oxygen species (ROS) scavenger glutathione (GSH) has been identified as a hallmark of renal cell carcinoma (RCC). The proposed mechanism for increased GSH levels is to counteract damaging ROS to sustain the
Meierhofer, David, Xiao, Yi
core   +2 more sources

Measurement of autophagy flux in benign prostatic hyperplasia in vitro

open access: yesProstate International, 2020
: Background: Recent studies have suggested a novel therapeutic strategy for treatment of benign prostatic hyperplasia (BPH) via modulation of autophagy.
Sung-hee Oh   +4 more
doaj   +1 more source

Blunting ROS/TRPML1 pathway protects AFB1-induced porcine intestinal epithelial cells apoptosis by restoring impaired autophagic flux

open access: yesEcotoxicology and Environmental Safety, 2023
Aflatoxin B1 (AFB1) is a stable mycotoxin that contaminates animal feed on a large scale and causes severe damage to intestinal cells, induces inflammation and stimulates autophagy.
Xinyi Cheng   +9 more
doaj   +1 more source

Enzyme localization can drastically affect signal amplification in signal transduction pathways [PDF]

open access: yes, 2005
Push-pull networks are ubiquitous in signal transduction pathways in both prokaryotic and eukaryotic cells. They allow cells to strongly amplify signals via the mechanism of zero-order ultrasensitivity.
van Albada, Siebe B.   +1 more
core   +5 more sources

Employment of fiber laser technology to weld austenitic stainless steel 304 l with aluminum alloy 5083 using pre-placed activating flux

open access: yesMaterials & Design, 2015
The overlapping welding was carried out in keyhole mode between austenitic stainless steel 304 l and aluminum alloy 5083 using a low power fiber laser in continuous irradiation.
M.A. Ezazi   +4 more
doaj   +1 more source

Olfactory modulation of flight in Drosophila is sensitive, selective and rapid [PDF]

open access: yes, 2010
Freely flying Drosophila melanogaster respond to odors by increasing their flight speed and turning upwind. Both these flight behaviors can be recapitulated in a tethered fly, which permits the odor stimulus to be precisely controlled.
Ashburner   +47 more
core   +3 more sources

Physical properties of voltage gated pores [PDF]

open access: yes, 2018
Experiments on single ionic channels have contributed to a large extent to our current view on the function of cell membrane. In these experiments the main observables are the physical quantities: ionic concentration, membrane electrostatic potential and
Ramírez de la Piscina Millán, Laureano   +1 more
core   +2 more sources

Magnetic Flux Loss and Flux Transport in a Decaying Active Region [PDF]

open access: yesThe Astrophysical Journal, 2008
16 pages, 7 figures, Accepted for publication in ...
Kubo, M.   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy