Results 71 to 80 of about 153,708 (298)

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Weld formation and microstructure properties in laser welding of TC4 titanium alloy with activating fluxes of oxides and chlorides

Cailiao gongcheng
SiO2， TiO2， NaCl， and KCl are chosen as activating fluxes for laser welding of 5 mm thick TC4 titanium alloy to increase the laser absorptivity of base material and improve weld formation.
HOU Jijun, DONG Junhui, WU Xiaofang
doaj   +1 more source

Pulsed Feedback Defers Cellular Differentiation [PDF]

, 2012
Environmental signals induce diverse cellular differentiation programs. In certain systems, cells defer differentiation for extended time periods after the signal appears, proliferating through multiple rounds of cell division before committing to a new ...
A Chastanet, A Eldar, A. D Grossman, A. H Singh, A. L Sonenshein, B. A Lazazzera, C. M Waters, D Burbulys, D Lopez, D Lopez, D. B Kearns, E Kussell, F Giudicelli, G. M Suel, G. M Suel, J Newport, J Newport, J. E Donnellan Jr, J. E Gonzalez-Pastor, J. E Segall, J. M Sterlini, J. R LeDeaux, J. W Veening, J. W Veening, Joe H. Levine, Jonathan Dworkin, K Asai, K Ireton, K. L Ohlsen, L Cai, M Acar, M Acar, M Fujita, M Fujita, M Jiang, M Perego, M Perego, M Raff, M Ratnayake-Lecamwasam, M Strauch, M. A Strauch, M. A Strauch, M. B Elowitz, Michael B. Elowitz, Michael Laub, Michelle E. Fontes, N Rosenfeld, N Rosenfeld, N. Q Balaban, P Eswaramoorthy, P Eswaramoorthy, T Long, T. Y Tsai, U Alon, V Molle, W. F Burkholder, Y. T Maeda   +56 more
core   +4 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Integrated Atom Detector Based on Field Ionization near Carbon Nanotubes

, 2009
We demonstrate an atom detector based on field ionization and subsequent ion counting. We make use of field enhancement near tips of carbon nanotubes to reach extreme electrostatic field values of up to 9x10^9 V/m, which ionize ground state rubidium ...
A. Günther, A. Stibor, B. Grüner, D. Kern, D. Lide, G. Visanescu, H. Beckey, J. D. Jackson, J. Fortágh, M. Häffner, M. Jag, W. Ketterle   +11 more
core   +1 more source

Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models. [PDF]

, 2016
Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes
Ahmed, Mohamed, Al-Abed, Yousef, Coleman, Thomas, Lakshminrusimha, Satyanarayana, Patel, Hardik, VanPatten, Sonya   +5 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Optogenetic stimulation inhibits the self-renewal of mouse embryonic stem cells

Cell & Bioscience, 2019
Modulation of the embryonic stem cell state is beneficial for elucidating the innate mechanisms of development and regenerative medicine. Ion flux plays important roles in modulating the transition between stemness and differentiation in mouse embryonic ...
Shaojun Wang, Lu Du, Guang-Hua Peng
doaj   +1 more source

An Overview of Inside-Out Planet Formation

, 2015
The Kepler-discovered Systems with Tightly-packed Inner Planets (STIPs), typically with several planets of Earth to super-Earth masses on well-aligned, sub-AU orbits may host the most common type of planets, including habitable planets, in the Galaxy ...
Chatterjee, Sourav, Hu, Xiao, Mohanty, Subhanjoy, Tan, Jonathan C., Zhu, Zhaohuan   +4 more
core   +1 more source

Sodium leak through K2P potassium channels and cardiac arrhythmia, an emerging theme. [PDF]

, 2017
In this issue of EMBO Molecular Medicine, Decher et al (2017) identify a point mutation in the K2P2 (TREK‐1) potassium (K+) channel that changes function in just those ways expected to predispose to right ventricular outflow tract (RVOT) ventricular
Goldstein, Steve An
core   +2 more sources