Results 81 to 90 of about 153,708 (298)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Pressure effects on bimolecular recombination and unimolecular dissociation reactions [PDF]
, 2001 The treatment of pressure effects on bimolecular recombinations and unimolecular dissociations is discussed. The analysis of recombination and dissociation reactions is made by showing how the nonequilibrium energy (E) and angular momentum (J)-dependent ...
Gao, Yi Qin, Marcus, R. A.
core +1 more source
Neutron flux perturbation in activation analysis
The International Journal of Applied Radiation and Isotopes, 1963 Abstract Some effects of the physical characteristics of samples and comparators in activation analysis have been evaluated in an experimental program. Induced specific activities in dilute aqueous solutions were compared with those in solid elements or compounds irradiated under the same conditions.
S.A. Reynolds, W.T. Mullins
openaire +3 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Pulsatile Hormonal Signaling to Extracellular Signal-Regulated Kinase: Exploring System Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency and Width [PDF]
, 2014 Gonadotropin-releasing hormone (GnRH) is secreted in brief pulses that stimulate synthesis and secretion of pituitary gonadotropin hormones and thereby mediate control of reproduction.
Armstrong +41 more
core +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Influence of the impurities on the depth of penetration with carbon steel weldings
Metalurgija, 2014 In this paper the results of the research about the influence of the impurities on the depth of penetration with carbon steels weldings of different chemical composition are presented.
O. Savytsky +3 more
doaj
Assessing methods to quantitatively validate TGFβ-dependent autophagy
Biology Open, 2020 Transforming growth factor beta (TGFβ) promotes tumorigenesis by suppressing immune surveillance and inducing epithelial to mesenchymal transition (EMT).
Charles B. Trelford +1 more
doaj +1 more source
Monte Carlo transition probabilities [PDF]
, 2001 Transition probabilities governing the interaction of energy packets and matter are derived that allow Monte Carlo NLTE transfer codes to be constructed without simplifying the treatment of line formation.
Abbott +14 more
core +3 more sources