Results 31 to 40 of about 2,095,505 (265)
Interrogating ligand-receptor interactions using highly sensitive cellular biosensors
Nature Communications, 2023 Interactions of membrane-resident proteins are important targets for therapeutic interventions but most methods to study them are either costly, laborious or fail to reflect the physiologic interaction of membrane resident proteins in trans.
Maximilian A. Funk +10 more
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Activation of hypoxia inducible factor 1 is a general phenomenon in infections with human pathogens [PDF]
, 2010 Background: Hypoxia inducible factor (HIF)-1 is the key transcriptional factor involved in the adaptation process of cells and organisms to hypoxia. Recent findings suggest that HIF-1 plays also a crucial role in inflammatory and infectious diseases ...
Peschel, Andreas +39 more
core +2 more sources
B cells extract antigens at Arp2/3-generated actin foci interspersed with linear filaments
eLife, 2019 Antibody production depends on B cell internalization and presentation of antigens to helper T cells. To acquire antigens displayed by antigen-presenting cells, B cells form immune synapses and extract antigens by the mechanical activity of the acto ...
Sophie I Roper +5 more
doaj +1 more source
Indonesian Journal of Business and EntrepreneurshipThis research aims to investigate the influence of Business Model Canvas (BMC) knowledge on entrepreneurial knowledge among young generations in the Jabodetabek region.
Nur Hendrasto +4 more
doaj +1 more source
New Directions in Transition Metal Catalyzed Carbonylation Chemistry
CHIMIA, 2018 Carbon monoxide (CO) represents an important C1-building block for the construction of some of the most fundamental chemical functionalities carrying a carbon–oxygen double bond.
Dennis U. Nielsen +2 more
doaj +1 more source
A Mouse Model to Study the Pathogenesis of γ-herpesviral Infections in Germinal Center B Cells
Cells, 2023 CD30-positive germinal center (GC)-derived B cell lymphomas are frequently linked to Epstein–Barr Virus (EBV) infection. However, a suitable animal model for the investigation of the interplay between γ-herpesvirus and host cells in B cell pathogenesis ...
Ursula Rambold +8 more
doaj +1 more source
Inter-agency co-operation in activation: comparing three vanguard ‘active’ welfare states [PDF]
, 2008 New forms of inter-agency co-operation have gained increasing prominence in the development and delivery of activation strategies. This article compares different models of inter-agency co-operation, drawing on case study research in Denmark, the ...
Lindsay, Colin, McQuaid, Ronald
core +3 more sources
Clinical and Developmental Immunology, 2013 Microglia are intrinsic components of the central nervous system (CNS). During pathologies in mammals, inflammatory processes implicate the resident microglia and the infiltration of blood cells including macrophages.
Françoise Le Marrec-Croq +4 more
doaj +1 more source
Active voice, active writing [PDF]
Ubiquity, 2020 Each "Communication Corner" essay is self-contained; however, they build on each other. For best results, before reading this essay and doing the exercise, go to the first essay "How an Ugly Duckling Became a Swan," then read each succeeding essay. Knowing when to write in the active or passive voice can fundamentally improve your work, but ...
openaire +2 more sources
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia. [PDF]
, 2014 The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity are typical features of neurodegenerative diseases, for example, Alzheimer's and Parkinson's diseases. An unexpected role of caspase-
Rodhe, J +11 more
core +1 more source